Paul W. Lenkowski, Ph.D.
Affiliations: | 2004 | University of Virginia, Charlottesville, VA |
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Parents
Sign in to add mentor| Milton Brown | grad student | 2004 | UVA | |
| (Mechanistic studies of novel sodium channel blockers.) | ||||
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Publications
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| Lenkowski PW, Batts TW, Smith MD, et al. (2007) A pharmacophore derived phenytoin analogue with increased affinity for slow inactivated sodium channels exhibits a desired anticonvulsant profile. Neuropharmacology. 52: 1044-54 |
| Ko SH, Jochnowitz N, Lenkowski PW, et al. (2006) Reversal of neuropathic pain by alpha-hydroxyphenylamide: a novel sodium channel antagonist. Neuropharmacology. 50: 865-73 |
| Yu EJ, Ko SH, Lenkowski PW, et al. (2005) Distinct domains of the sodium channel beta3-subunit modulate channel-gating kinetics and subcellular location. The Biochemical Journal. 392: 519-26 |
| Lenkowski PW, Ko SH, Anderson JD, et al. (2004) Block of human NaV1.5 sodium channels by novel alpha-hydroxyphenylamide analogues of phenytoin. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 21: 635-44 |
| Schenck HA, Lenkowski PW, Choudhury-Mukherjee I, et al. (2004) Design, synthesis and evaluation of novel hydroxyamides as orally available anticonvulsants. Bioorganic & Medicinal Chemistry. 12: 979-93 |
| Anderson JD, Hansen TP, Lenkowski PW, et al. (2003) Voltage-gated sodium channel blockers as cytostatic inhibitors of the androgen-independent prostate cancer cell line PC-3. Molecular Cancer Therapeutics. 2: 1149-54 |
| Lenkowski PW, Shah BS, Dinn AE, et al. (2003) Lidocaine block of neonatal Nav1.3 is differentially modulated by co-expression of beta1 and beta3 subunits. European Journal of Pharmacology. 467: 23-30 |