Kai Y. Kwok, Ph.D.

Affiliations: 
2001 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
non-viral gene delivery systems
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"Kai Kwok"
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Kevin G. Rice grad student 2001 University of Michigan
 (An investigation of sulfhydryl cross -linked DNA delivery systems for liver targeted gene therapy.)
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Publications

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Kwok KY, Park Y, Yang Y, et al. (2003) In vivo gene transfer using sulfhydryl cross-linked PEG-peptide/glycopeptide DNA co-condensates. Journal of Pharmaceutical Sciences. 92: 1174-85
Park Y, Kwok KY, Boukarim C, et al. (2002) Synthesis of sulfhydryl cross-linking poly(ethylene glycol)-peptides and glycopeptides as carriers for gene delivery. Bioconjugate Chemistry. 13: 232-9
Kwok KY, Yang Y, Rice KG. (2001) Evolution of cross-linked non-viral gene delivery systems. Current Opinion in Molecular Therapeutics. 3: 142-6
McKenzie DL, Smiley E, Kwok KY, et al. (2000) Low molecular weight disulfide cross-linking peptides as nonviral gene delivery carriers. Bioconjugate Chemistry. 11: 901-9
Kwok KY, Adami RC, Hester KC, et al. (2000) Strategies for maintaining the particle size of peptide DNA condensates following freeze-drying. International Journal of Pharmaceutics. 203: 81-8
McKenzie DL, Kwok KY, Rice KG. (2000) A potent new class of reductively activated peptide gene delivery agents. The Journal of Biological Chemistry. 275: 9970-7
Collard WT, Yang Y, Kwok KY, et al. (2000) Biodistribution, metabolism, and in vivo gene expression of low molecular weight glycopeptide polyethylene glycol peptide DNA co-condensates. Journal of Pharmaceutical Sciences. 89: 499-512
Kwok KY, McKenzie DL, Evers DL, et al. (1999) Formulation of highly soluble poly(ethylene glycol)-peptide DNA condensates. Journal of Pharmaceutical Sciences. 88: 996-1003
Terebesi J, Kwok KY, Rice KG. (1998) Iodinated plasmid DNA as a tool for studying gene delivery. Analytical Biochemistry. 263: 120-3
Adami RC, Collard WT, Gupta SA, et al. (1998) Stability of peptide-condensed plasmid DNA formulations. Journal of Pharmaceutical Sciences. 87: 678-83
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