Thomas De Luca, Ph.D.

Affiliations: 
2009 Foods and Nutrition Purdue University, West Lafayette, IN, United States 
Area:
NADH oxidases of the cell surface
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"Thomas De Luca"
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D. James Morré grad student 2009 Purdue
 (Cytosolic NADH as an intracellular modulator of sphingolipid-mediated apoptosis by inhibitors of a cell-surface tumor-associated NADH oxidase.)
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Publications

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Di Martile M, Desideri M, De Luca T, et al. (2016) Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells Oncotarget. 7: 11332-11348
Del Bufalo D, Desideri M, De Luca T, et al. (2014) Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer Molecular Cancer. 13
Ragazzoni Y, Desideri M, Gabellini C, et al. (2013) The thiazole derivative CPTH6 impairs autophagy Cell Death & Disease. 4
Wu LY, De Luca T, Watanabe T, et al. (2011) Metabolite modulation of HeLa cell response to ENOX2 inhibitors EGCG and phenoxodiol. Biochimica Et Biophysica Acta. 1810: 784-9
De Luca T, Morré DM, Morré DJ. (2010) Reciprocal relationship between cytosolic NADH and ENOX2 inhibition triggers sphingolipid-induced apoptosis in HeLa cells. Journal of Cellular Biochemistry. 110: 1504-11
De Luca T, Bosneaga E, Morré DM, et al. (2008) Downstream targets of altered sphingolipid metabolism in response to inhibition of ENOX2 by phenoxodiol. Biofactors (Oxford, England). 34: 253-60
De Luca T, Morré DM, Zhao H, et al. (2005) NAD+/NADH and/or CoQ/CoQH2 ratios from plasma membrane electron transport may determine ceramide and sphingosine-1-phosphate levels accompanying G1 arrest and apoptosis. Biofactors (Oxford, England). 25: 43-60
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