Michael J. Heffernan, Ph.D.

Affiliations: 
2008 Georgia Institute of Technology, Atlanta, GA 
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"Michael Heffernan"
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Niren Murthy grad student 2008 Georgia Tech
 (Biodegradable polymeric delivery systems for protein subunit vaccines.)
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Publications

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Wang Q, Barry MA, Seid CA, et al. (2017) 3M-052 as an adjuvant for a PLGA microparticle-based Leishmania donovani recombinant protein vaccine. Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Barry MA, Wang Q, Jones KM, et al. (2016) A therapeutic nanoparticle vaccine against Trypanosoma cruzi in a BALB/c mouse model of Chagas disease. Human Vaccines & Immunotherapeutics. 0
Hudspeth EM, Wang Q, Seid CA, et al. (2016) Expression and Purification of an Engineered, Yeast-expressed Leishmania donovani Nucleoside Hydrolase with Immunogenic Properties. Human Vaccines & Immunotherapeutics. 0
Wang Q, Tan MT, Keegan BP, et al. (2014) Time course study of the antigen-specific immune response to a PLGA microparticle vaccine formulation. Biomaterials. 35: 8385-93
Hotez PJ, Dumonteil E, Heffernan MJ, et al. (2013) Innovation for the 'bottom 100 million': eliminating neglected tropical diseases in the Americas. Advances in Experimental Medicine and Biology. 764: 1-12
Dumonteil E, Bottazzi ME, Zhan B, et al. (2012) Accelerating the development of a therapeutic vaccine for human Chagas disease: rationale and prospects. Expert Review of Vaccines. 11: 1043-55
Heffernan MJ, Zaharoff DA, Fallon JK, et al. (2011) In vivo efficacy of a chitosan/IL-12 adjuvant system for protein-based vaccines. Biomaterials. 32: 926-32
Heffernan MJ, Murthy N. (2009) Disulfide-crosslinked polyion micelles for delivery of protein therapeutics. Annals of Biomedical Engineering. 37: 1993-2002
Heffernan MJ, Kasturi SP, Yang SC, et al. (2009) The stimulation of CD8+ T cells by dendritic cells pulsed with polyketal microparticles containing ion-paired protein antigen and poly(inosinic acid)-poly(cytidylic acid). Biomaterials. 30: 910-8
Lee S, Yang SC, Heffernan MJ, et al. (2007) Polyketal microparticles: a new delivery vehicle for superoxide dismutase. Bioconjugate Chemistry. 18: 4-7
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