Joseph Bryan, PhD, University of Pennsylvania
Affiliations: | Cell Biology | Pacific Northwest Diabetes Research Institute, Seattle, WA, United States |
Area:
Cell BiologyWebsite:
http://www.pnri.org/research-programs/bryan-lab/bio/Google:
"Joseph Bryan"Bio:
http://www.gradprofiles.com/baylor-coll-med-physiology.html
Mean distance: 15.69 (cluster 28) | S | N | B | C | P |
Cross-listing: Cell Biology Tree
Children
Sign in to add trainee| Robert A Edwards | grad student | 1991-1995 | Baylor College of Medicine (Cell Biology Tree) |
| George Perry | post-doc | 1979-1982 | |
| Lynne M. Coluccio | post-doc | 1985-1986 | Baylor College of Medicine (Cell Biology Tree) |
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Publications
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| Sikimic J, McMillen TS, Bleile C, et al. (2018) ATP-binding without hydrolysis switches sulfonylurea receptor 1 (SUR1) to outward-facing conformations that activate K channels. The Journal of Biological Chemistry |
| Kurland DB, Gerzanich V, Karimy JK, et al. (2016) The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia. Journal of Neuroinflammation. 13: 130 |
| Ortiz D, Bryan J. (2015) Neonatal Diabetes and Congenital Hyperinsulinism Caused by Mutations in ABCC8/SUR1 are Associated with Altered and Opposite Affinities for ATP and ADP. Frontiers in Endocrinology. 6: 48 |
| Nakamura Y, Bryan J. (2014) Targeting SUR1/Abcc8-type neuroendocrine KATP channels in pancreatic islet cells. Plos One. 9: e91525 |
| Ortiz D, Gossack L, Quast U, et al. (2013) Reinterpreting the action of ATP analogs on K(ATP) channels. The Journal of Biological Chemistry. 288: 18894-902 |
| Ortiz D, Voyvodic P, Gossack L, et al. (2012) Two neonatal diabetes mutations on transmembrane helix 15 of SUR1 increase affinity for ATP and ADP at nucleotide binding domain 2. The Journal of Biological Chemistry. 287: 17985-95 |
| Su Y, Lam TK, He W, et al. (2012) Hypothalamic leucine metabolism regulates liver glucose production. Diabetes. 61: 85-93 |
| Winkler M, Kühner P, Russ U, et al. (2012) Role of the amino-terminal transmembrane domain of sulfonylurea receptor SUR2B for coupling to K(IR)6.2, ligand binding, and oligomerization. Naunyn-Schmiedeberg's Archives of Pharmacology. 385: 287-98 |
| Kühner P, Prager R, Stephan D, et al. (2012) Importance of the Kir6.2 N-terminus for the interaction of glibenclamide and repaglinide with the pancreatic K(ATP) channel. Naunyn-Schmiedeberg's Archives of Pharmacology. 385: 299-311 |
| Gier B, Krippeit-Drews P, Sheiko T, et al. (2009) Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress. The Journal of Clinical Investigation. 119: 3246-56 |