Harold G. Martinson

Affiliations: 
Chemistry University of California, Los Angeles, Los Angeles, CA 
Area:
Biochemistry
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"Harold Martinson"
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Children

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Moses V. Chao grad student 1976-1980 (Neurotree)
Steven J. Kim grad student 2001 UCLA
Noh J. Park grad student 2004 UCLA
Anita Nag grad student 2007 UCLA
Amir Kazerouninia grad student 2008 UCLA
Frank W. Rigo Nusser grad student 2008 UCLA
Benson Ngo grad student 2012 UCLA
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Publications

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Zhang H, Rigo F, Martinson HG. (2015) Poly(A) Signal-Dependent Transcription Termination Occurs through a Conformational Change Mechanism that Does Not Require Cleavage at the Poly(A) Site. Molecular Cell
Tsao DC, Park NJ, Nag A, et al. (2012) Prolonged α-amanitin treatment of cells for studying mutated polymerases causes degradation of DSIF160 and other proteins. Rna (New York, N.Y.). 18: 222-9
Martinson HG. (2011) An active role for splicing in 3'-end formation. Wiley Interdisciplinary Reviews. Rna. 2: 459-70
Kazerouninia A, Ngo B, Martinson HG. (2010) Poly(A) signal-dependent degradation of unprocessed nascent transcripts accompanies poly(A) signal-dependent transcriptional pausing in vitro. Rna (New York, N.Y.). 16: 197-210
Rigo F, Martinson HG. (2009) Polyadenylation releases mRNA from RNA polymerase II in a process that is licensed by splicing. Rna (New York, N.Y.). 15: 823-36
Rigo F, Martinson HG. (2008) Functional coupling of last-intron splicing and 3'-end processing to transcription in vitro: the poly(A) signal couples to splicing before committing to cleavage. Molecular and Cellular Biology. 28: 849-62
Nag A, Narsinh K, Martinson HG. (2007) The poly(A)-dependent transcriptional pause is mediated by CPSF acting on the body of the polymerase. Nature Structural & Molecular Biology. 14: 662-9
Nag A, Narsinh K, Kazerouninia A, et al. (2006) The conserved AAUAAA hexamer of the poly(A) signal can act alone to trigger a stable decrease in RNA polymerase II transcription velocity. Rna (New York, N.Y.). 12: 1534-44
Rigo F, Kazerouninia A, Nag A, et al. (2005) The RNA tether from the poly(A) signal to the polymerase mediates coupling of transcription to cleavage and polyadenylation. Molecular Cell. 20: 733-45
Park NJ, Tsao DC, Martinson HG. (2004) The two steps of poly(A)-dependent termination, pausing and release, can be uncoupled by truncation of the RNA polymerase II carboxyl-terminal repeat domain. Molecular and Cellular Biology. 24: 4092-103
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