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Wayne W. Poon, Ph.D.

Affiliations: 
2001 University of California, Los Angeles, Los Angeles, CA 
Area:
Biochemistry, Chemical Biology, Proteomics and Bioinformatics, Systems Biology and Biological Regulation, Metabolism, Aging and Development
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"Wayne Poon"
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Parents

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Catherine F. Clarke grad student 2001 UCLA
 (Studies on ubiquinone biosynthesis in Escherichia coli and Saccharomyces cerevisiae.)
Carl W. Cotman post-doc UC Irvine (Neurotree)

Children

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Publications

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Sims R, van der Lee SJ, Naj AC, et al. (2017) Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics
Pensalfini A, Albay R, Rasool S, et al. (2014) Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques. Neurobiology of Disease. 71: 53-61
Nelson PT, Estus S, Abner EL, et al. (2014) ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta Neuropathologica. 127: 825-43
Rohn TT, Day RJ, Sheffield CB, et al. (2014) Apolipoprotein E pathology in vascular dementia. International Journal of Clinical and Experimental Pathology. 7: 938-47
Rohn TT, Day RJ, Catlin LW, et al. (2013) Immunolocalization of an amino-terminal fragment of apolipoprotein E in the Pick's disease brain. Plos One. 8: e80180
Poon WW, Carlos AJ, Aguilar BL, et al. (2013) β-Amyloid (Aβ) oligomers impair brain-derived neurotrophic factor retrograde trafficking by down-regulating ubiquitin C-terminal hydrolase, UCH-L1. The Journal of Biological Chemistry. 288: 16937-48
Tai LM, Bilousova T, Jungbauer L, et al. (2013) Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples. The Journal of Biological Chemistry. 288: 5914-26
Rohn TT, Catlin LW, Poon WW. (2013) Caspase-cleaved glial fibrillary acidic protein within cerebellar white matter of the Alzheimer's disease brain. International Journal of Clinical and Experimental Pathology. 6: 41-8
Kim HJ, Park JW, Byun JH, et al. (2012) Quantitative analysis of axonal transport by using compartmentalized and surface micropatterned culture of neurons. Acs Chemical Neuroscience. 3: 433-8
Henkins KM, Sokolow S, Miller CA, et al. (2012) Extensive p-tau pathology and SDS-stable p-tau oligomers in Alzheimer's cortical synapses. Brain Pathology (Zurich, Switzerland). 22: 826-33
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