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Ossama B. Kashlan, Ph.D.

Affiliations: 
2002 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biological
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"Ossama Kashlan"
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Barry S. Cooperman grad student 2002 Penn
 (A comprehensive model for the allosteric regulation of mammalian ribonucleotide reductase.)

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Wang X, Ertem M, McKernan AS, et al. (2020) Bile Acids Directly Bind ENaC and Allosterically Regulate its Activity The Faseb Journal. 34: 1-1
Passero CJ, Carattino MD, Kashlan OB, et al. (2010) Defining an inhibitory domain in the gamma subunit of the epithelial sodium channel. American Journal of Physiology. Renal Physiology. 299: F854-61
Cooperman BS, Gao Y, Tan C, et al. (2005) Peptide inhibitors of mammalian ribonucleotide reductase. Advances in Enzyme Regulation. 45: 112-25
Radivoyevitch T, Kashlan OB, Cooperman BS. (2005) Rational polynomial representation of ribonucleotide reductase activity. Bmc Biochemistry. 6: 8
He J, Roy B, Périgaud C, et al. (2005) The enantioselectivities of the active and allosteric sites of mammalian ribonucleotide reductase. The Febs Journal. 272: 1236-42
Gao Y, Kashlan OB, Kaur J, et al. (2005) Mechanisms of action of peptide inhibitors of mammalian ribonucleotide reductase targeting quaternary structure. Biopolymers. 80: 9-17
Cooperman BS, Kashlan OB. (2003) A comprehensive model for the allosteric regulation of Class Ia ribonucleotide reductases. Advances in Enzyme Regulation. 43: 167-82
Kashlan OB, Cooperman BS. (2003) Comprehensive model for allosteric regulation of mammalian ribonucleotide reductase: refinements and consequences. Biochemistry. 42: 1696-706
Kashlan OB, Scott CP, Lear JD, et al. (2002) A comprehensive model for the allosteric regulation of mammalian ribonucleotide reductase. Functional consequences of ATP- and dATP-induced oligomerization of the large subunit. Biochemistry. 41: 462-74
Scott CP, Kashlan OB, Lear JD, et al. (2001) A quantitative model for allosteric control of purine reduction by murine ribonucleotide reductase. Biochemistry. 40: 1651-61
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