Hyuk-Soo Seo, Ph.D.
Affiliations: | 2004 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
BiologicalGoogle:
"Hyuk-Soo Seo"Mean distance: 8.86 | S | N | B | C | P |
Parents
Sign in to add mentorBarry S. Cooperman | grad student | 2004 | Penn | |
(Studies on the dynamic nature of GTPase activation center of Escherichia coli ribosomes using chemical probes and fast kinetics.) |
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Publications
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Fan M, Lu W, Che J, et al. (2022) Covalent disruptor of YAP-TEAD association suppresses defective hippo signaling. Elife. 11 |
Pinch BJ, Doctor ZM, Nabet B, et al. (2020) Identification of a potent and selective covalent Pin1 inhibitor. Nature Chemical Biology |
Harvey EP, Hauseman ZJ, Cohen DT, et al. (2020) Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering. Cell Chemical Biology |
Ben-Nun Y, Seo HS, Harvey EP, et al. (2020) Identification of a Structural Determinant for Selective Targeting of HDMX. Structure (London, England : 1993) |
Manz TD, Sivakumaren SC, Ferguson FM, et al. (2020) Discovery and Structure-Activity Relationship Study of (Z)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. Journal of Medicinal Chemistry |
Manz TD, Sivakumaren SC, Yasgar A, et al. (2020) Structure-Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. Acs Medicinal Chemistry Letters. 11: 346-352 |
Sivakumaren SC, Shim H, Zhang T, et al. (2020) Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors. Cell Chemical Biology |
Blus BJ, Koh J, Krolak A, et al. (2019) Allosteric modulation of nucleoporin assemblies by intrinsically disordered regions. Science Advances. 5: eaax1836 |
Valencia AM, Collings CK, Dao HT, et al. (2019) Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling. Cell |
de Araujo ED, Orlova A, Neubauer HA, et al. (2019) Structural Implications of STAT3 and STAT5 SH2 Domain Mutations. Cancers. 11 |