Ian S. Farrell, Ph.D.

Affiliations: 
2011 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biological
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Barry S. Cooperman grad student 2011 Penn
 (Investigating tRNA release from the bacterial ribosome.)
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Publications

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Plochowietz A, Farrell I, Smilansky Z, et al. (2016) In vivo single-RNA tracking shows that most tRNA diffuses freely in live bacteria. Nucleic Acids Research
Chen C, Cui X, Beausang JF, et al. (2016) Elongation factor G initiates translocation through a power stroke. Proceedings of the National Academy of Sciences of the United States of America
Henley R, Ashcroft BA, Farrell I, et al. (2015) Electrophoretic Deformation of Individual Transfer RNA Molecules Reveals Their Identity. Nano Letters
Liu J, Pampillo M, Guo F, et al. (2014) Monitoring collagen synthesis in fibroblasts using fluorescently labeled tRNA pairs. Journal of Cellular Physiology. 229: 1121-9
Barhoom S, Farrell I, Shai B, et al. (2013) Dicodon monitoring of protein synthesis (DiCoMPS) reveals levels of synthesis of a viral protein in single cells. Nucleic Acids Research. 41: e177
Chen C, Zhang H, Broitman SL, et al. (2013) Dynamics of translation by single ribosomes through mRNA secondary structures. Nature Structural & Molecular Biology. 20: 582-8
Stevens B, Chen C, Farrell I, et al. (2012) FRET-based identification of mRNAs undergoing translation. Plos One. 7: e38344
Stevens B, Chen C, Farrell I, et al. (2012) Single FV and VF events detected by FRET between Cy3-F and Cy5-V during translation of mRNA-1 (FV: A, B) and mRNA-2 (VF: C, D). Plos One
Chen C, Zhang H, Broitman SL, et al. (2012) Translation by Single Ribosomes Through mRNA Secondary Structures Biophysical Journal. 102: 67a-68a
Mandecki W, Bharill S, Borejdo J, et al. (2008) Fluorescence enhancement on silver nanostructures: Studies of components of ribosomal translation in vitro Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6862
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