Orlando D. Schärer

Affiliations: 
Chemistry Stony Brook University, Stony Brook, NY, United States 
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"Orlando Schärer"
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Children

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The V. Ho grad student 2009 SUNY Stony Brook
Angelo Guainazzi grad student 2010 SUNY Stony Brook
Barbara Orelli grad student 2010 SUNY Stony Brook
Adebanke F. Fagbemi grad student 2011 SUNY Stony Brook
Jung-Eun Yeo grad student 2011 SUNY Stony Brook
Jerome Gualbert grad student 2012 SUNY Stony Brook
Yan Su grad student 2012 SUNY Stony Brook
Shivam Mukherjee grad student 2014 SUNY Stony Brook
Jawad Alzeer research scientist 2000-2010 Universität Zürich
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Publications

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Pizzolato J, Mukherjee S, Schärer OD, et al. (2015) FANCD2-associated Nuclease 1, but Not Exonuclease 1 or Flap Endonuclease 1, Is Able to Unhook DNA Interstrand Cross-links in Vitro. The Journal of Biological Chemistry. 290: 22602-11
Mukherjee S, Guainazzi A, Schärer OD. (2014) Synthesis of structurally diverse major groove DNA interstrand crosslinks using three different aldehyde precursors. Nucleic Acids Research. 42: 7429-35
Hodskinson MR, Silhan J, Crossan GP, et al. (2014) Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair. Molecular Cell. 54: 472-84
Clauson C, Schärer OD, Niedernhofer L. (2013) Advances in understanding the complex mechanisms of DNA interstrand cross-link repair. Cold Spring Harbor Perspectives in Biology. 5: a012732
Schärer OD. (2013) Nucleotide excision repair in eukaryotes. Cold Spring Harbor Perspectives in Biology. 5: a012609
Wickramaratne S, Mukherjee S, Villalta PW, et al. (2013) Synthesis of sequence-specific DNA-protein conjugates via a reductive amination strategy. Bioconjugate Chemistry. 24: 1496-506
Bogliolo M, Schuster B, Stoepker C, et al. (2013) Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia. American Journal of Human Genetics. 92: 800-6
Slean MM, Reddy K, Wu B, et al. (2013) Interconverting conformations of slipped-DNA junctions formed by trinucleotide repeats affect repair outcome. Biochemistry. 52: 773-85
Yeo JE, Khoo A, Fagbemi AF, et al. (2012) The efficiencies of damage recognition and excision correlate with duplex destabilization induced by acetylaminofluorene adducts in human nucleotide excision repair. Chemical Research in Toxicology. 25: 2462-8
Knipscheer P, Räschle M, Schärer OD, et al. (2012) Replication-coupled DNA interstrand cross-link repair in Xenopus egg extracts. Methods in Molecular Biology (Clifton, N.J.). 920: 221-43
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