Rory Curtis

Affiliations: 
Elixir Pharmaceuticals, Cambridge, MA, United States 
Area:
GAP43, glia, ion channels, regeneration, neurotrophins, GAP-43
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"Rory Curtis"
Bio:

Email: rorycurtis@comcast.net ............ History: PhD, Biochemistry, Imperial College, London, UK;
Post-doc, Regeneron Pharmaceuticals, NY;
Lecturer, Bristol University, Bristol, UK;
Senior Scientist, Millennium Pharmaceuticals, MA;
Senior Director, Elixir Pharmaceuticals, MA;

Mean distance: 14.95 (cluster 11)
 
SNBCP
Cross-listing: Neurotree

Parents

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Michael R. Hanley research assistant 1985-1987 Imperial College London
Graham P. Wilkin grad student 1985-1991 Imperial College London (Neurotree)
Peter S. DiStefano post-doc 1991-1995 Regeneron Pharmaceuticals
Ronald M. Lindsay post-doc 1991-1995 Regeneron Pharmaceuticals (Neurotree)

Children

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Scott Eliasof research scientist 2000-2001 Millennium Pharmaceuticals (Neurotree)
Tara M. D'Eon research scientist 2006-2007 Elixir Pharmaceuticals (Neurotree)
Julie Huber research scientist 2002-2008 Elixir Pharmaceuticals

Collaborators

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William A. Catterall collaborator Wahington University (Neurotree)
David E. Clapham collaborator Harvard Medical School/HHMI
Susan M. Hall collaborator Guy's Hospital, London (Neurotree)
Mats H. Holmqvist collaborator Millennium Pharmaceuticals (Neurotree)
Krisjan Jessen collaborator UCL (Neurotree)
Irwin Levitan collaborator Boston University, Brandeis University
Rhona Mirsky collaborator UCL (Neurotree)
John V. Priestley collaborator Thomas's Hospital, London (Neurotree)
Steven S. Scherer collaborator Penn (Neurotree)
Immaculada Silos-Santiago collaborator Millennium Pharmaceuticals
Barbara A. Spruce collaborator Imperial College, London (Neurotree)
Helen Stewart collaborator UCL (Neurotree)
Carlos Ibanez collaborator 1993-1995 Regeneron Pharmaceuticals (Neurotree)
David Wynick collaborator 1995-1997 University of Bristol (Neurotree)
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Publications

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Caneba CA, Yang L, Baddour J, et al. (2014) Nitric oxide is a positive regulator of the Warburg effect in ovarian cancer cells. Cell Death & Disease. 5: e1302
Longo KA, Govek EK, Nolan A, et al. (2012) Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity (Journal of Pharmacology and Experimental Therapeutics (2011) 339, (115-124)) Journal of Pharmacology and Experimental Therapeutics. 340: 810
Longo KA, Govek EK, Nolan A, et al. (2011) Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity. The Journal of Pharmacology and Experimental Therapeutics. 339: 115-24
Medina-Gomez G, Gray SL, Yetukuri L, et al. (2007) PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism. Plos Genetics. 3: e64
DiStefano PS, Curtis R, Geddes BJ. (2007) Insulin resistance, glycemic control and adiposity: key determinants of healthy lifespan. Current Alzheimer Research. 4: 153-7
Curtis R, O'Connor G, DiStefano PS. (2006) Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways. Aging Cell. 5: 119-26
Solomon JM, Pasupuleti R, Xu L, et al. (2006) Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Molecular and Cellular Biology. 26: 28-38
Napper AD, Hixon J, McDonagh T, et al. (2005) Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. Journal of Medicinal Chemistry. 48: 8045-54
McDonagh T, Hixon J, DiStefano PS, et al. (2005) Microplate filtration assay for nicotinamide release from NAD using a boronic acid resin. Methods (San Diego, Calif.). 36: 346-50
Lelliott CJ, López M, Curtis RK, et al. (2005) Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1108-19
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