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Mark R. Kelley

Affiliations: 
Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Molecular Biology, Biochemistry
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"Mark Kelley"
Mean distance: 9953.25
 
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Melissa M. Limp-Foster grad student 2001 Indiana University
Mikael Rinne grad student 2004 Indiana University
Aditi A. Bapat grad student 2009 Indiana University

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Publications

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Gampala S, Moon HR, Wireman R, et al. (2024) New Ref-1/APE1 targeted inhibitors demonstrating improved potency for clinical applications in multiple cancer types. Pharmacological Research. 107092
Mijit M, Boner M, Cordova RA, et al. (2023) Activation of the integrated stress response (ISR) pathways in response to Ref-1 inhibition in human pancreatic cancer and its tumor microenvironment. Frontiers in Medicine. 10: 1146115
Mijit M, Liu S, Sishtla K, et al. (2023) Identification of Novel Pathways Regulated by APE1/Ref-1 in Human Retinal Endothelial Cells. International Journal of Molecular Sciences. 24
Behrouzi A, Kelley MR, Fehrenbacher JC. (2022) Oxidative DNA Damage: A Role in Altering Neuronal Function. Journal of Cellular Signaling. 3: 160-166
Mijit M, Wireman R, Armstrong L, et al. (2022) RelA Is an Essential Target for Enhancing Cellular Responses to the DNA Repair/Ref-1 Redox Signaling Protein and Restoring Perturbated Cellular Redox Homeostasis in Mouse PDAC Cells. Frontiers in Oncology. 12: 826617
Behrouzi A, Xia H, Thompson EL, et al. (2022) Oxidative DNA Damage and Cisplatin Neurotoxicity Is Exacerbated by Inhibition of OGG1 Glycosylase Activity and APE1 Endonuclease Activity in Sensory Neurons. International Journal of Molecular Sciences. 23
Gampala S, Shah F, Lu X, et al. (2021) Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target. Journal of Experimental & Clinical Cancer Research : Cr. 40: 251
Caston RA, Gampala S, Armstrong L, et al. (2020) The multifunctional APE1 DNA repair-redox signaling protein as a drug target in human disease. Drug Discovery Today
Sahakian L, Filippone RT, Stavely R, et al. (2020) Inhibition of APE1/Ref-1 Redox Signaling Alleviates Intestinal Dysfunction and Damage to Myenteric Neurons in a Mouse Model of Spontaneous Chronic Colitis. Inflammatory Bowel Diseases
Codrich M, Comelli M, Malfatti MC, et al. (2019) Inhibition of APE1-endonuclease activity affects cell metabolism in colon cancer cells via a p53-dependent pathway. Dna Repair. 82: 102675
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