Lauren M. Congdon, Ph.D.

Affiliations: 
2012 Genetic, Molecular, and Cell Biology University of Southern California, Los Angeles, CA, United States 
Area:
Molecular Biology, Biochemistry
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"Lauren Congdon"

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Judd C. Rice grad student 2012 USC
 (Multiple functions of the PR-Set7 histone methyltransferase: From transcription to the cell cycle.)
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Publications

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Tuzon CT, Spektor T, Kong X, et al. (2014) Concerted activities of distinct H4K20 methyltransferases at DNA double-strand breaks regulate 53BP1 nucleation and NHEJ-directed repair. Cell Reports. 8: 430-8
Congdon LM, Sims JK, Tuzon CT, et al. (2014) The PR-Set7 binding domain of Riz1 is required for the H4K20me1-H3K9me1 trans-tail 'histone code' and Riz1 tumor suppressor function. Nucleic Acids Research. 42: 3580-9
Tuzon CT, Spektor TM, Congdon LM, et al. (2014) Abstract LB-133: Orchestrated recruitment of histone methyltransferases to DNA double strand breaks facilitates 53BP1 binding and proficient repair Cancer Research. 74
Spektor TM, Congdon LM, Veerappan CS, et al. (2011) The UBC9 E2 SUMO conjugating enzyme binds the PR-Set7 histone methyltransferase to facilitate target gene repression. Plos One. 6: e22785
Wu S, Wang W, Kong X, et al. (2010) Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression. Genes & Development. 24: 2531-42
Congdon LM, Houston SI, Veerappan CS, et al. (2010) PR-Set7-mediated monomethylation of histone H4 lysine 20 at specific genomic regions induces transcriptional repression. Journal of Cellular Biochemistry. 110: 609-19
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