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Amal M. Youssef, Ph.D.

Affiliations: 
2001 Virginia Commonwealth University, Richmond, VA, United States 
Area:
Pharmaceutical Chemistry
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"Amal Youssef"
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Donald J. Abraham grad student 2001 VCU
 (Synthesis, computer-aided drug design, and QSAR studies of chiral allosteric modifiers of hemoglobin.)

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Publications

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Atatreh N, Youssef AM, Ghattas MA, et al. (2019) Anti-inflammatory drug approach: Synthesis and biological evaluation of novel pyrazolo[3,4-d]pyrimidine compounds. Bioorganic Chemistry. 86: 393-400
Malki A, Elbayaa RY, Ali O, et al. (2017) Novel quinuclidinone derivatives induced apoptosis in human breast cancer via targeting p53. Bioorganic Chemistry. 72: 57-63
Elzahhar PA, Soliman R, El-Hawash SA, et al. (2015) Design, synthesis and antimicrobial evaluation of methyl pyridyl-2,4- dioxobutanoates and some new derived ring systems. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 11: 407-14
Malki A, Elbayaa RY, Ashour HM, et al. (2015) Novel thiosemicarbazides induced apoptosis in human MCF-7 breast cancer cells via JNK signaling. Journal of Enzyme Inhibition and Medicinal Chemistry. 30: 786-95
El-Hawash SA, Soliman R, Youssef AM, et al. (2014) Design, synthesis and biological screening of some pyridinylpyrazole and pyridinylisoxazole derivatives as potential anti-inflammatory, analgesic, antipyretic and antimicrobial agents. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 10: 318-38
Youssef AM, Malki A, Badr MH, et al. (2012) Synthesis and anticancer activity of novel benzimidazole and benzothiazole derivatives against HepG2 liver cancer cells. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 8: 151-62
Rida SM, Youssef AM, Badr MH, et al. (2012) Design, synthesis and evaluation of novel benzimidazoles, benzothiazoles and benzofurans incorporating pyrazole moiety as antiangiogenic agents. Arzneimittel-Forschung. 62: 63-74
Masoud GN, Youssef AM, Abdel Khalek MM, et al. (2012) Design, synthesis, and biological evaluation of new 4-thiazolidinone derivatives substituted with benzimidazole ring as potential chemotherapeutic agents Medicinal Chemistry Research. 22: 707-725
Hashioka S, McLarnon JG, Ryu JK, et al. (2011) Pyrazole compound 2-MBAPA as a novel inhibitor of microglial activation and neurotoxicity in vitro and in vivo. Journal of Alzheimer's Disease : Jad. 27: 531-41
Youssef AM, Neeland EG, Villanueva EB, et al. (2010) Synthesis and biological evaluation of novel pyrazole compounds. Bioorganic & Medicinal Chemistry. 18: 5685-96
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