Fred W. Perrino
Affiliations: | Wake Forest University School of Medicine, Winston-Salem, NC, United States |
Area:
BiochemistryGoogle:
"Fred Perrino"Mean distance: 13271
Children
Sign in to add trainee| Daniel J. Mazur | grad student | 2000 | Wake Forest School of Medicine |
| Matthew G. Pence | grad student | 2009 | Wake Forest School of Medicine |
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Publications
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| Amico G, Hemphill WO, Severino M, et al. (2022) Genotype-Phenotype Correlation and Functional Insights for Two Monoallelic Missense Variants Affecting the Catalytic Core. Genes. 13 |
| Venkatadri R, Sabapathy V, Dogan M, et al. (2022) Targeting Bcl6 in the TREX1 D18N murine model ameliorates autoimmunity by modulating T follicular helper cells and Germinal center B cells. European Journal of Immunology |
| Hemphill WO, Simpson SR, Liu M, et al. (2021) TREX1 as a Novel Immunotherapeutic Target. Frontiers in Immunology. 12: 660184 |
| Simpson SR, Hemphill WO, Hudson T, et al. (2020) TREX1 - Apex predator of cytosolic DNA metabolism. Dna Repair. 94: 102894 |
| Hemphill W, Harvey S, Gumpena R, et al. (2020) Small Molecule TREX1 Inhibitors as Novel Immunotherapies The Faseb Journal. 34: 1-1 |
| Simpson SR, Rego SL, Harvey SE, et al. (2019) T Cells Produce IFN-α in the TREX1 D18N Model of Lupus-like Autoimmunity. Journal of Immunology (Baltimore, Md. : 1950) |
| Hemphill WO, Perrino FW. (2019) Measuring TREX1 and TREX2 exonuclease activities. Methods in Enzymology. 625: 109-133 |
| Simpson S, Rego S, Harvey S, et al. (2019) 284 T cells produce interferon alpha in a model of lupus-like disease Lupus Science & Medicine. 6 |
| Rego SL, Harvey S, Simpson SR, et al. (2018) TREX1 D18N mice fail to process erythroblast DNA resulting in inflammation and dysfunctional erythropoiesis. Autoimmunity. 1-12 |
| Rego SL, Harvey S, Simpson SR, et al. (2018) Abstract 501: Anemia of Inflammation in an Exonuclease Deficient Lupus Mouse Circulation Research. 123 |