Patrick J. Grohar, Ph.D.
Affiliations: | 2001 | Wayne State University, Detroit, MI, United States |
Area:
Biochemistry, Organic ChemistryGoogle:
"Patrick Grohar"Mean distance: 3619.36
Parents
Sign in to add mentor| Christine S. Chow | grad student | 2001 | Wayne State | |
| (Synthesis, investigation and application of modified nucleic acids.) | ||||
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Publications
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| Deng Q, Natesan R, Cidre-Aranaz F, et al. (2022) Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1. Cell Reports. 39: 110971 |
| Gedminas JM, Kaufman R, Boguslawski EA, et al. (2022) Lurbinectedin inhibits the EWS-WT1 transcription factor in desmoplastic small round cell tumor. Molecular Cancer Therapeutics |
| Gedminas JM, Chasse MH, McBrairty M, et al. (2020) Desmoplastic small round cell tumor is dependent on the EWS-WT1 transcription factor. Oncogenesis. 9: 41 |
| Flores G, Everett JH, Boguslawski EA, et al. (2020) CDK9 Blockade Exploits Context-Dependent Transcriptional Changes to Improve Activity and Limit Toxicity of Mithramycin for Ewing Sarcoma. Molecular Cancer Therapeutics |
| Sissung TM, Huang PA, Hauke RJ, et al. (2019) Severe Hepatotoxicity of Mithramycin Therapy Caused by Altering Expression of Hepatocellular Bile Transporters. Molecular Pharmacology |
| Bailey K, Cost C, Davis I, et al. (2019) Emerging novel agents for patients with advanced Ewing sarcoma: a report from the Children's Oncology Group (COG) New Agents for Ewing Sarcoma Task Force. F1000research. 8 |
| Harlow ML, Chasse MH, Boguslawski EA, et al. (2019) Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule Dependent Manner. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research |
| Flores G, Kitchen-Goosen S, Oswald B, et al. (2019) Abstract 2882: Mithramycin impedes EWS-FLI1 driven transcription by preventing target promoter clearance Cancer Research |
| Chasse MH, Boguslawski E, Sorensen K, et al. (2019) Abstract 2883: Mithramycin inhibits KDM6A (UTX) and SWI/SNF to induce apoptosis in malignant rhabdoid tumor Cancer Research. 79: 2883-2883 |
| Chasse MH, Boguslawski EA, Sorensen KM, et al. (2018) Abstract A32: Therapeutically targeting PRC2 expression and dynamics in rhabdoid tumor Cancer Research. 78 |