Chamila N. Rupasinghe, Ph.D.
Affiliations: | 2008 | Chemistry | Wayne State University, Detroit, MI, United States |
Area:
Biochemistry, Organic ChemistryGoogle:
"Chamila Rupasinghe"Mean distance: 3619.36
Parents
Sign in to add mentor| Christine S. Chow | grad student | 2008 | Wayne State | |
| (Peptide ligand design, synthesis and development of assays for PDZ domain proteins and RNA.) | ||||
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Publications
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| Marshall J, Wong KY, Rupasinghe CN, et al. (2015) Inhibition of N-Methyl-D-Aspartate-Induced Retinal Neuronal Death by Polyarginine Peptides is Linked to the Attenuation of Stress-Induced Hyperpolarization of the Inner Mitochondrial Membrane Potential. The Journal of Biological Chemistry |
| Bucur O, Gaidos G, Yatawara A, et al. (2015) A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death. Scientific Reports. 5: 9893 |
| Patra CR, Rupasinghe CN, Dutta SK, et al. (2015) Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer. Acs Chemical Biology |
| Yatawara A, Gaidos G, Rupasinghe CN, et al. (2015) Small-molecule inhibitors of JC polyomavirus infection. Journal of Peptide Science : An Official Publication of the European Peptide Society. 21: 236-42 |
| Yu J, Rupasinghe C, Wilson JL, et al. (2015) Targeting receptor tyrosine kinases and their downstream signaling with cell-penetrating peptides in human pulmonary artery smooth muscle and endothelial cells. Chemical Biology & Drug Design. 85: 586-97 |
| Green DS, Rupasinghe C, Warburton R, et al. (2013) A cell permeable peptide targeting the intracellular loop 2 of endothelin B receptor reduces pulmonary hypertension in a hypoxic rat model. Plos One. 8: e81309 |
| Pennarun B, Gaidos G, Bucur O, et al. (2013) killerFLIP: a novel lytic peptide specifically inducing cancer cell death. Cell Death & Disease. 4: e894 |
| Kaur M, Rupasinghe CN, Klosi E, et al. (2013) Selection of heptapeptides that bind helix 69 of bacterial 23S ribosomal RNA. Bioorganic & Medicinal Chemistry. 21: 1240-7 |
| Sallum CO, Wilson JL, Rupasinghe C, et al. (2012) Enhancing and limiting endothelin-1 signaling with a cell-penetrating peptide mimicking the third intracellular loop of the ETB receptor. Chemical Biology & Drug Design. 80: 374-81 |
| Patra CR, Rupasinghe CN, Dutta SK, et al. (2012) Chemically modified peptides targeting the PDZ domain of GIPC as a therapeutic approach for cancer. Acs Chemical Biology. 7: 770-9 |