William G. Dunphy

California Institute of Technology, Pasadena, CA 
Cell Biology, Genetics, Biochemistry
"William Dunphy"
Mean distance: 39813


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James E. Rothman grad student Caltech
John Newport post-doc Caltech (Cell Biology Tree)


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Daniel A. Gold grad student 2010 Caltech
Juan S. Ramirez-Lugo grad student 2010 Caltech
BETA: Related publications


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Ryu H, Yoshida MM, Sridharan V, et al. (2015) SUMOylation of the C-terminal domain of DNA topoisomerase IIα regulates the centromeric localization of Claspin. Cell Cycle (Georgetown, Tex.). 14: 2777-84
Guo C, Kumagai A, Schlacher K, et al. (2015) Interaction of Chk1 with Treslin negatively regulates the initiation of chromosomal DNA replication. Molecular Cell. 57: 492-505
Lee J, Dunphy WG. (2013) The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks. Molecular Biology of the Cell. 24: 1343-53
Kumar S, Yoo HY, Kumagai A, et al. (2012) Role for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extracts. Cell Cycle (Georgetown, Tex.). 11: 1183-94
Meng Z, Capalbo L, Glover DM, et al. (2011) Role for casein kinase 1 in the phosphorylation of Claspin on critical residues necessary for the activation of Chk1. Molecular Biology of the Cell. 22: 2834-47
Kumagai A, Shevchenko A, Shevchenko A, et al. (2011) Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication. The Journal of Cell Biology. 193: 995-1007
Ramírez-Lugo JS, Yoo HY, Yoon SJ, et al. (2011) CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts. Cell Cycle (Georgetown, Tex.). 10: 469-80
Wawrousek KE, Fortini BK, Polaczek P, et al. (2010) Xenopus DNA2 is a helicase/nuclease that is found in complexes with replication proteins And-1/Ctf4 and Mcm10 and DSB response proteins Nbs1 and ATM. Cell Cycle (Georgetown, Tex.). 9: 1156-66
Gold DA, Dunphy WG. (2010) Drf1-dependent kinase interacts with Claspin through a conserved protein motif. The Journal of Biological Chemistry. 285: 12638-46
Kumagai A, Shevchenko A, Shevchenko A, et al. (2010) Treslin collaborates with TopBP1 in triggering the initiation of DNA replication. Cell. 140: 349-59
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