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John J. Perona

Affiliations: 
University of California, Santa Barbara, Santa Barbara, CA, United States 
Area:
Biochemistry
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"John Perona"
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Parents

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Dieter Söll grad student
Thomas A. Steitz grad student Yale
Charles S. Craik post-doc UCSF

Children

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Tracy A. Nissan grad student 2001 UC Santa Barbara
Kate J. Newberry grad student 2002 UC Santa Barbara
Luke D. Sherlin grad student 2002 UC Santa Barbara
David A. Hiller grad student 2005 UC Santa Barbara
Nathan T. Uter grad student 2005 UC Santa Barbara
Stephanie S. de los Rios grad student 2006 UC Santa Barbara
Scott I. Hauenstein grad student 2007 UC Santa Barbara
Eleonora M. Corigliano grad student 2008 UC Santa Barbara
Sheena R. Menezes grad student 2011 UC Santa Barbara
Annia Rodriguez Hernandez grad student 2011 UC Santa Barbara
Javin P. Oza grad student 2012 UC Santa Barbara
Ita Gruić-Sovulj post-doc 2005 University of California

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Publications

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Gottfried-Lee I, Perona JJ, Karplus PA, et al. (2022) Structures of Pyrrolysine tRNA-Synthetases Support the Need for De Novo Selections When Altering the Substrate Specificity. Acs Chemical Biology
Avila-Crump S, Hemshorn ML, Jones CM, et al. (2022) Generating Efficient Pyrrolysyl-tRNA Synthetases for Structurally Diverse Non-Canonical Amino Acids. Acs Chemical Biology
Miller DV, Rauch BJ, Harich K, et al. (2018) Promiscuity of methionine salvage pathway enzymes in Methanocaldococcus jannaschii. Microbiology (Reading, England)
Sungwienwong I, Hostetler ZM, Blizzard RJ, et al. (2017) Improving target amino acid selectivity in a permissive aminoacyl tRNA synthetase through counter-selection. Organic & Biomolecular Chemistry
Rauch BJ, Klimek J, David LL, et al. (2017) Persulfide formation mediates cysteine and homocysteine biosynthesis in Methanosarcina acetivorans. Biochemistry
Rauch BJ, Perona JJ. (2016) Efficient sulfide assimilation in Methanosarcina acetivorans is mediated by the MA1715 protein. Journal of Bacteriology
Rauch BJ, Porter JJ, Mehl RA, et al. (2015) Improved incorporation of noncanonical amino acids by an engineered tRNATyr suppressor. Biochemistry
Rauch BJ, Gustafson A, Perona JJ. (2014) Novel proteins for homocysteine biosynthesis in anaerobic microorganisms Molecular Microbiology. 94: 1330-1342
Hadd A, Perona JJ. (2014) Recoding aminoacyl-tRNA synthetases for synthetic biology by rational protein-RNA engineering. Acs Chemical Biology. 9: 2761-6
Dulic M, Perona JJ, Gruic-Sovulj I. (2014) Determinants for tRNA-dependent pretransfer editing in the synthetic site of isoleucyl-tRNA synthetase. Biochemistry. 53: 6189-98
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