Henry I. Mosberg

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Biochemistry
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"Henry Mosberg"
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Publications

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Henry S, Anand JP, Brinkel AC, et al. (2020) SAR Matrices Enable Discovery of Mixed Efficacy μ-Opioid Receptor Agonist Peptidomimetics with Simplified Structures through an Aromatic-Amine Pharmacophore. Acs Chemical Neuroscience
Montgomery D, Anand JP, Baber MA, et al. (2019) Structure-Activity Relationships of 7-Substituted Dimethyltyrosine-Tetrahydroisoquinoline Opioid Peptidomimetics. Molecules (Basel, Switzerland). 24
Henry S, Fernandez TM, Anand JP, et al. (2019) Structural Simplification of a Tetrahydroquinoline Core Peptidomimetic µ-Opioid-Receptor (MOR) Agonist/ δ-Opioid Receptor (DOR) Antagonist Produces Improved Metabolic Stability  . Journal of Medicinal Chemistry
Nastase AF, Anand JP, Bender AM, et al. (2019) Dual Pharmacophores Explored via Structure-Activity Relationship (SAR) Matrix: Insights into Potent, Bifunctional Opioid Ligand Design. Journal of Medicinal Chemistry
Nastase AF, Griggs NW, Anand JP, et al. (2018) Synthesis and pharmacological evaluation of novel C-8 substituted tetrahydroquinolines as balanced-affinity mu/delta opioid ligands for the treatment of pain. Acs Chemical Neuroscience
Anand JP, Kochan KE, Nastase AF, et al. (2018) In Vivo Effects of μ Opioid Receptor Agonist/δ Opioid Receptor Antagonist Peptidomimetics Following Acute and Repeated Administration. British Journal of Pharmacology
Harland AA, Bender AM, Griggs NW, et al. (2016) Effects of N-Substitutions on the Tetrahydroquinoline (THQ) core of Mixed-Efficacy μ-Opioid Receptor (MOR)/ δ-Opioid Receptor (DOR) Ligands. Journal of Medicinal Chemistry
Anand JP, Boyer BT, Mosberg HI, et al. (2016) The behavioral effects of a mixed efficacy antinociceptive peptide, VRP26, following chronic administration in mice. Psychopharmacology
Bender AM, Griggs NW, Gao C, et al. (2015) Rapid Synthesis of Boc-2',6'-dimethyl-l-tyrosine and Derivatives and Incorporation into Opioid Peptidomimetics. Acs Medicinal Chemistry Letters. 6: 1199-203
Harland AA, Yeomans L, Griggs NW, et al. (2015) Further Optimization and Evaluation of Bioavailable, Mixed-Efficacy μ-Opioid Receptor (MOR) Agonists/ δ-Opioid Receptor (DOR) Antagonists: Balancing MOR and DOR Affinities. Journal of Medicinal Chemistry
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