Scott A. Tobler, Ph.D.

Affiliations: 
2002 University of Virginia, Charlottesville, VA 
Area:
Chemical Engineering, Biochemistry
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"Scott Tobler"
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Erik J. Fernandez grad student 2002 UVA
 (Structural, kinetic, and thermodynamic features of protein aggregation revealed by hydrogen exchange and mass spectrometry.)
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Publications

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Kelley BD, Tobler SA, Brown P, et al. (2008) Weak partitioning chromatography for anion exchange purification of monoclonal antibodies. Biotechnology and Bioengineering. 101: 553-66
Fernandez EJ, Tobler SA. (2006) Elucidating structure, stability, and conformational distributions during protein aggregation with hydrogen exchange and mass spectrometry Misbehaving Proteins: Protein (Mis)Folding, Aggregation, and Stability. 81-98
Tobler SA, Holmes BW, Cromwell ME, et al. (2004) Benzyl alcohol-induced destabilization of interferon-gamma: a study by hydrogen-deuterium isotope exchange. Journal of Pharmaceutical Sciences. 93: 1605-17
Wang SS, Tobler SA, Good TA, et al. (2003) Hydrogen exchange-mass spectrometry analysis of beta-amyloid peptide structure. Biochemistry. 42: 9507-14
Tobler SA, Fernandez EJ. (2002) Structural features of interferon-gamma aggregation revealed by hydrogen exchange. Protein Science : a Publication of the Protein Society. 11: 1340-52
Chang ST, Tobler SA, Fernandez EJ. (2001) Unfolding and conformational distributions during protein precipitation. Biotechnology Progress. 17: 583-5
Tobler SA, Sherman NE, Fernandez EJ. (2000) Tracking lysozyme unfolding during salt-induced precipitation with hydrogen exchange and mass spectrometry. Biotechnology and Bioengineering. 71: 194-207
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