Jacob L. Jordan, Ph.D.

Affiliations: 
2009 University of Virginia, Charlottesville, VA 
Area:
Chemical Engineering, Biochemistry, General Biophysics
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"Jacob Jordan"
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Parents

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Erik J. Fernandez grad student 2009 UVA
 (Applying computational tools to improve stability and reduce aggregate formation of proteins.)
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Publications

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Weiss WF, Zhang A, Ivanova MI, et al. (2014) Reduction of the C191-C220 disulfide of α-chymotrypsinogen A reduces nucleation barriers for aggregation. Biophysical Chemistry. 185: 79-87
Brummitt RK, Andrews JM, Jordan JL, et al. (2012) Thermodynamics of amyloid dissociation provide insights into aggregate stability regimes. Biophysical Chemistry. 168: 10-8
Sahin E, Jordan JL, Spatara ML, et al. (2011) Computational design and biophysical characterization of aggregation-resistant point mutations for γD crystallin illustrate a balance of conformational stability and intrinsic aggregation propensity. Biochemistry. 50: 628-39
Zhang A, Jordan JL, Ivanova MI, et al. (2010) Molecular level insights into thermally induced α-chymotrypsinogen A amyloid aggregation mechanism and semiflexible protofibril morphology. Biochemistry. 49: 10553-64
Jordan JL, Arndt JW, Hanf K, et al. (2009) Structural understanding of stabilization patterns in engineered bispecific Ig-like antibody molecules. Proteins. 77: 832-41
Jordan JL, Fernandez EJ. (2008) QCM-D sensitivity to protein adsorption reversibility. Biotechnology and Bioengineering. 101: 837-42
Yan D, Jordan JL, Burapatana V, et al. (2003) Formation of n-alkanethiolate self-assembled monolayers onto gold in aqueous micellar solutions of n-alkyltrimethylammonium bromides Langmuir. 19: 3357-3364
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