Nirjal Bhattarai, Ph.D.

Affiliations: 
2013 Molecular & Cell Biology University of Iowa, Iowa City, IA 
Area:
Virology Biology
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"Nirjal Bhattarai"

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Jack T. Stapleton grad student 2013 University of Iowa
 (GB virus C interactions with HIV: Effects on immunoactivation and mechanisms of immunomodulation.)
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Publications

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Lamture G, Baer A, Fischer JW, et al. (2021) TCR-independent Activation in Presence of a Src-family Kinase Inhibitor Improves CAR-T Cell Product Attributes. Journal of Immunotherapy (Hagerstown, Md. : 1997)
Colon-Moran W, Baer A, Lamture G, et al. (2021) A short hepatitis C virus NS5A peptide expression by AAV vector modulates human T cell activation and reduces vector immunogenicity. Gene Therapy
Baer A, Colon-Moran W, Bhattarai N. (2018) Characterization of the effects of immunomodulatory drug fingolimod (FTY720) on human T cell receptor signaling pathways. Scientific Reports. 8: 10910
Baer A, Colon-Moran W, Xiang J, et al. (2017) Src-family kinases negatively regulate NFAT signaling in resting human T cells. Plos One. 12: e0187123
McLinden JH, Bhattarai N, Stapleton JT, et al. (2017) Yellow fever virus, but not Zika or Dengue virus inhibits T cell receptor-mediated T cell function by an RNA-based mechanism. The Journal of Infectious Diseases
Bhattarai N, McLinden JH, Xiang J, et al. (2017) Hepatitis C virus infection inhibits a Src-kinase regulatory phosphatase and reduces T cell activation in vivo. Plos Pathogens. 13: e1006232
Bhattarai N, McLinden JH, Xiang J, et al. (2015) Conserved Motifs within Hepatitis C Virus Envelope (E2) RNA and Protein Independently Inhibit T Cell Activation. Plos Pathogens. 11: e1005183
Chivero ET, Bhattarai N, McLinden JH, et al. (2015) Human Pegivirus (HPgV; formerly known as GBV-C) inhibits IL-12 dependent natural killer cell function. Virology. 485: 116-127
Chivero ET, Bhattarai N, McLinden JH, et al. (2015) Human Pegivirus (HPgV; formerly known as GBV-C) inhibits IL-12 dependent natural killer cell function Virology. 485: 116-127
Stapleton JT, Xiang J, McLinden JH, et al. (2014) A novel T cell evasion mechanism in persistent RNA virus infection. Transactions of the American Clinical and Climatological Association. 125: 14-24; discussion 24
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