Kathleen M. Holtz, Ph.D.

2000 Boston College, Newton, MA, United States 
"Kathleen Holtz"
Mean distance: 5687.57


Sign in to add mentor
Evan R. Kantrowitz grad student 2000 Boston College
 (Investigating mechanistic details in the catalytic reaction of alkaline phosphatase from Escherichia coli.)
BETA: Related publications


You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Stec B, Holtz KM, Wojciechowski CL, et al. (2005) Structure of the wild-type TEM-1 beta-lactamase at 1.55 A and the mutant enzyme Ser70Ala at 2.1 A suggest the mode of noncovalent catalysis for the mutant enzyme. Acta Crystallographica. Section D, Biological Crystallography. 61: 1072-9
Holtz KM, Catrina IE, Hengge AC, et al. (2000) Mutation of Arg-166 of alkaline phosphatase alters the thio effect but not the transition state for phosphoryl transfer. Implications for the interpretation of thio effects in reactions of phosphatases. Biochemistry. 39: 9451-8
Stec B, Holtz KM, Kantrowitz ER. (2000) A revised mechanism for the alkaline phosphatase reaction involving three metal ions. Journal of Molecular Biology. 299: 1303-11
Holtz KM, Stec B, Myers JK, et al. (2000) Alternate modes of binding in two crystal structures of alkaline phosphatase-inhibitor complexes. Protein Science : a Publication of the Protein Society. 9: 907-15
Holtz KM, Kantrowitz ER. (1999) The mechanism of the alkaline phosphatase reaction: insights from NMR, crystallography and site-specific mutagenesis. Febs Letters. 462: 7-11
Holtz KM, Stec B, Kantrowitz ER. (1999) A model of the transition state in the alkaline phosphatase reaction. The Journal of Biological Chemistry. 274: 8351-4
Widlanski TS, Myers JK, Stec B, et al. (1997) The road less travelled: taming phosphatases. Chemistry & Biology. 4: 489-92
See more...