James P. Cardia, Ph.D.
Affiliations: | 2006 | Boston College, Newton, MA, United States |
Area:
BiochemistryGoogle:
"James Cardia"Mean distance: 5687.57
Parents
Sign in to add mentor| Evan R. Kantrowitz | grad student | 2006 | Boston College | |
| (Structural effects upon ligand binding to the allosteric enzyme aspartate transcarbamoylase.) | ||||
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Publications
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| Cardia JP, Eldo J, Xia J, et al. (2008) Use of L-asparagine and N-phosphonacetyl-L-asparagine to investigate the linkage of catalysis and homotropic cooperativity in E. coli aspartate transcarbomoylase. Proteins. 71: 1088-96 |
| Eldo J, Cardia JP, O'Day EM, et al. (2006) N-phosphonacetyl-L-isoasparagine a potent and specific inhibitor of Escherichia coli aspartate transcarbamoylase. Journal of Medicinal Chemistry. 49: 5932-8 |
| Heng S, Stieglitz KA, Eldo J, et al. (2006) T-state inhibitors of E. coli aspartate transcarbamoylase that prevent the allosteric transition. Biochemistry. 45: 10062-71 |
| Stieglitz KA, Dusinberre KJ, Cardia JP, et al. (2005) Structure of the E.coli aspartate transcarbamoylase trapped in the middle of the catalytic cycle. Journal of Molecular Biology. 352: 478-86 |
| Wang J, Stieglitz KA, Cardia JP, et al. (2005) Structural basis for ordered substrate binding and cooperativity in aspartate transcarbamoylase. Proceedings of the National Academy of Sciences of the United States of America. 102: 8881-6 |
| Wojciechowski CL, Cardia JP, Kantrowitz ER. (2002) Alkaline phosphatase from the hyperthermophilic bacterium T. maritima requires cobalt for activity. Protein Science : a Publication of the Protein Society. 11: 903-11 |