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Jaewoo Choi, Ph.D.

Affiliations: 
2010 Chemistry Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
Organic Chemistry
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"Jaewoo Choi"
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Robert G. Salomon grad student Case Western
Robert G. Salomon grad student 2010 Case Western
 (Part I: Total syntheses of novel oxidatively-truncated phosphatidylserines. Part II: A nonenzymatic route to lysophosphatidylcholine: Spontaneous deacylation of oxidatively damaged phospholipids.)

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Publications

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Li C, Zhang WJ, Choi J, et al. (2016) Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase. Redox Biology. 9: 220-228
Wang H, Linetsky M, Guo J, et al. (2015) 4-Hydroxy-7-oxo-5-heptenoic Acid (HOHA) Lactone is a Biologically Active Precursor for the Generation of 2-(ω-Carboxyethyl)pyrrole (CEP) Derivatives of Proteins and Ethanolamine Phospholipids. Chemical Research in Toxicology. 28: 967-77
Gu X, Zhang W, Choi J, et al. (2011) An (1)O2 route to γ-hydroxyalkenal phospholipids by vitamin E-induced fragmentation of hydroperoxydiene-derived endoperoxides. Chemical Research in Toxicology. 24: 1080-93
Choi J, Laird JM, Salomon RG. (2011) An efficient synthesis of γ-hydroxy-α,β-unsaturated aldehydic esters of 2-lysophosphatidylcholine. Bioorganic & Medicinal Chemistry. 19: 580-7
Choi J, Zhang W, Gu X, et al. (2011) Lysophosphatidylcholine is generated by spontaneous deacylation of oxidized phospholipids. Chemical Research in Toxicology. 24: 111-8
Mesaros C, Gugiu BG, Zhou R, et al. (2010) A 13-Oxo-9,10-epoxytridecenoate phospholipid analogue of the genotoxic 4,5-epoxy-2E-decenal: detection in vivo, chemical synthesis, and adduction with DNA. Chemical Research in Toxicology. 23: 516-27
Lu L, Gu X, Hong L, et al. (2009) Synthesis and structural characterization of carboxyethylpyrrole-modified proteins: mediators of age-related macular degeneration. Bioorganic & Medicinal Chemistry. 17: 7548-61
Ashraf MZ, Kar NS, Chen X, et al. (2008) Specific oxidized phospholipids inhibit scavenger receptor bi-mediated selective uptake of cholesteryl esters. The Journal of Biological Chemistry. 283: 10408-14
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