H Peter Spielmann

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
Biochemistry
Website:
https://biochemistry.med.uky.edu/users/hps
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"H Spielmann"
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Dissertation: https://digital.library.unt.edu/ark:/67531/metadc1280573/

Mean distance: 9953.25
 

Parents

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John E. Hearst grad student 1991 UC Berkeley
 (The application of psoralens to the study of DNA structure, function and dynamics.)
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Publications

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Rising KA, Crenshaw CM, Koo HJ, et al. (2015) Formation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase. Acs Chemical Biology. 10: 1729-36
Onono F, Subramanian T, Sunkara M, et al. (2013) Efficient use of exogenous isoprenols for protein isoprenylation by MDA-MB-231 cells is regulated independently of the mevalonate pathway. The Journal of Biological Chemistry. 288: 27444-55
Subramanian T, Parkin S, Spielmann HP. (2012) Synthesis of Farnesol Analogues Containing Triazoles in Place of Isoprenes through 'Click Chemistry' Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 23: 2539-2543
Subramanian T, Pais JE, Liu S, et al. (2012) Farnesyl diphosphate analogues with aryl moieties are efficient alternate substrates for protein farnesyltransferase. Biochemistry. 51: 8307-19
Chang SY, Hudon-Miller SE, Yang SH, et al. (2012) Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24. Journal of Lipid Research. 53: 1176-82
Adams VR, Deremer DL, Stevich B, et al. (2010) Anticancer activity of novel unnatural synthetic isoprenoids. Anticancer Research. 30: 2505-12
Davies BS, Barnes RH, Tu Y, et al. (2010) An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria. Human Molecular Genetics. 19: 2682-94
Miriyala S, Subramanian T, Panchatcharam M, et al. (2010) Functional characterization of the atypical integral membrane lipid phosphatase PDP1/PPAPDC2 identifies a pathway for interconversion of isoprenols and isoprenoid phosphates in mammalian cells. The Journal of Biological Chemistry. 285: 13918-29
Onono FO, Morgan MA, Spielmann HP, et al. (2010) A tagging-via-substrate approach to detect the farnesylated proteome using two-dimensional electrophoresis coupled with Western blotting. Molecular & Cellular Proteomics : McP. 9: 742-51
SHI YB, LIPSON SE, CHI DY, et al. (2010) ChemInform Abstract: Applications of Psoralens as Probes of Nucleic Acid Structure and Function Cheminform. 22: no-no
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