Peter J. Detloff

Affiliations: 
1993- Biochemistry and Molecular Genetics University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Genetics, Biochemistry
Website:
https://www.uab.edu/medicine/biochem/faculty/detloff
Google:
"Peter J Detloff"
Mean distance: 6635.5
 

Parents

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Thomas D. Petes grad student 1991 Chicago (Cell Biology Tree)
 (DNA repair during meiotic recombination in Saccharomyces Cerevisiae.)
Oliver Smithies post-doc 1990-1993 UNC Chapel Hill

Children

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Jamie A. Cearley grad student 2001 UAB
Chin-Hsing Lin grad student 2001 UAB
Oon T. Ang grad student 2002 UAB
Karen T. Dixon grad student 2004 UAB
Andrew B. Crouse grad student 2005 UAB
BETA: Related publications

Publications

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Kumar A, Zhang J, Tallaksen-Greene S, et al. (2016) Allelic Series of Huntington's Disease Knock-in Mice Reveals Expression Discorrelates. Human Molecular Genetics
Jin J, Peng Q, Hou Z, et al. (2015) Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease. Human Molecular Genetics. 24: 2508-27
Ciamei A, Detloff PJ, Morton AJ. (2015) Progression of behavioural despair in R6/2 and Hdh knock-in mouse models recapitulates depression in Huntington's disease Behavioural Brain Research. 291: 140-146
Sathasivam K, Neueder A, Gipson TA, et al. (2013) Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 2366-70
Dougherty SE, Reeves JL, Lesort M, et al. (2013) Purkinje cell dysfunction and loss in a knock-in mouse model of Huntington disease. Experimental Neurology. 240: 96-102
Kumar A, Kneynsberg A, Tucholski J, et al. (2012) Tissue transglutaminase overexpression does not modify the disease phenotype of the R6/2 mouse model of Huntington's disease. Experimental Neurology. 237: 78-89
Heng MY, Detloff PJ, Paulson HL, et al. (2010) Early alterations of autophagy in Huntington disease-like mice. Autophagy. 6: 1206-8
Heng MY, Duong DK, Albin RL, et al. (2010) Early autophagic response in a novel knock-in model of Huntington disease. Human Molecular Genetics. 19: 3702-20
Perry GM, Tallaksen-Greene S, Kumar A, et al. (2010) Mitochondrial calcium uptake capacity as a therapeutic target in the R6/2 mouse model of Huntington's disease. Human Molecular Genetics. 19: 3354-71
Heng MY, Detloff PJ, Wang PL, et al. (2009) In vivo evidence for NMDA receptor-mediated excitotoxicity in a murine genetic model of Huntington disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3200-5
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