Kareem A. Chehade, Ph.D.
Affiliations: | 2001 | University of Kentucky, Lexington, KY |
Area:
BiochemistryGoogle:
"Kareem Chehade"Mean distance: 13271
Parents
Sign in to add mentor| H Peter Spielmann | grad student | 2001 | University of Kentucky | |
| (Design, synthesis, and biochemical characterization of o-modified farnesyl pyrophosphate analogues.) | ||||
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| Rising KA, Crenshaw CM, Koo HJ, et al. (2015) Formation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase. Acs Chemical Biology. 10: 1729-36 |
| Roberts MJ, Troutman JM, Chehade KA, et al. (2006) Hydrophilic anilinogeranyl diphosphate prenyl analogues are Ras function inhibitors. Biochemistry. 45: 15862-72 |
| Troutman JM, Chehade KA, Kiegiel K, et al. (2004) Synthesis of acyloxymethyl ester prodrugs of the transferable protein farnesyl transferase substrate farnesyl methylenediphosphonate. Bioorganic & Medicinal Chemistry Letters. 14: 4979-82 |
| Chehade KA, Kiegiel K, Isaacs RJ, et al. (2002) Photoaffinity analogues of farnesyl pyrophosphate transferable by protein farnesyl transferase. Journal of the American Chemical Society. 124: 8206-19 |
| Micali E, Chehade KA, Isaacs RJ, et al. (2001) Protein farnesyltransferase isoprenoid substrate discrimination is dependent on isoprene double bonds and branched methyl groups. Biochemistry. 40: 12254-65 |
| Than C, Morimoto H, Williams PG, et al. (2001) Preparation, NMR characterization, and labeling reactions of tritiated triacetoxy sodium borohydride. The Journal of Organic Chemistry. 66: 3602-5 |
| Chehade KA, Spielmann HP. (2000) Facile and efficient synthesis of 4-azidotetrafluoroaniline: a new photoaffinity reagent. The Journal of Organic Chemistry. 65: 4949-53 |
| Chehade KA, Andres DA, Morimoto H, et al. (2000) Design and synthesis of a transferable farnesyl pyrophosphate analogue to Ras by protein farnesyltransferase. The Journal of Organic Chemistry. 65: 3027-33 |