Sarbjot S. Sachdeva, Ph.D.
Affiliations: | 2008 | Virginia Commonwealth University, Richmond, VA, United States |
Area:
Pharmaceutical Chemistry, BiochemistryGoogle:
"Sarbjot Sachdeva"Mean distance: 11375.1
Parents
Sign in to add mentor| Kevin A. Reynolds | grad student | 2008 | VCU | |
| (Interactions of mtFabH with its substrates and inhibitors reveal novel mechanistic insights.) | ||||
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Publications
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| Alhamadsheh MM, Waters NC, Sachdeva S, et al. (2008) Synthesis and biological evaluation of novel sulfonyl-naphthalene-1,4-diols as FabH inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 6402-5 |
| Sachdeva S, Reynolds KA. (2008) Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase III (mtFabH) assay: principles and method. Methods in Molecular Medicine. 142: 205-13 |
| Sachdeva S, Musayev FN, Alhamadsheh MM, et al. (2008) Separate entrance and exit portals for ligand traffic in Mycobacterium tuberculosis FabH. Chemistry & Biology. 15: 402-12 |
| Sachdeva S, Musayev F, Alhamadsheh MM, et al. (2008) Probing reactivity and substrate specificity of both subunits of the dimeric Mycobacterium tuberculosis FabH using alkyl-CoA disulfide inhibitors and acyl-CoA substrates. Bioorganic Chemistry. 36: 85-90 |
| Alhamadsheh MM, Musayev F, Komissarov AA, et al. (2007) Alkyl-CoA disulfides as inhibitors and mechanistic probes for FabH enzymes. Chemistry & Biology. 14: 513-24 |
| Musayev F, Sachdeva S, Scarsdale JN, et al. (2005) Crystal structure of a substrate complex of Mycobacterium tuberculosis β-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A Journal of Molecular Biology. 346: 1313-1321 |