Hak-Sung Kim

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1999-2003 Wonkwang University, Iksan, South Korea 
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"Hak-Sung Kim"
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Dunn PM, Kim HS, Jacobson KA, et al. (2004) Northern Ring Conformation of Methanocarba-Adenosine 5'-Triphosphate Required for Activation of P2X Receptors. Drug Development Research. 61: 227-232
Ohno M, Costanzi S, Kim HS, et al. (2004) Nucleotide analogues containing 2-oxa-bicyclo[2.2.1]heptane and l-alpha-threofuranosyl ring systems: interactions with P2Y receptors. Bioorganic & Medicinal Chemistry. 12: 5619-30
Kim HS, Ohno M, Xu B, et al. (2003) 2-Substitution of adenine nucleotide analogues containing a bicyclo[3.1.0]hexane ring system locked in a northern conformation: enhanced potency as P2Y1 receptor antagonists. Journal of Medicinal Chemistry. 46: 4974-87
Choi Y, George C, Comin MJ, et al. (2003) A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude. Journal of Medicinal Chemistry. 46: 3292-9
Kim HS, Jacobson KA. (2003) Synthesis of a novel conformationally locked carbocyclic nucleoside ring system. Organic Letters. 5: 1665-8
Xu B, Stephens A, Kirschenheuter G, et al. (2002) Acyclic analogues of adenosine bisphosphates as P2Y receptor antagonists: phosphate substitution leads to multiple pathways of inhibition of platelet aggregation. Journal of Medicinal Chemistry. 45: 5694-709
Waldo GL, Corbitt J, Boyer JL, et al. (2002) Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist. Molecular Pharmacology. 62: 1249-57
Kim SA, Marshall MA, Melman N, et al. (2002) Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions. Journal of Medicinal Chemistry. 45: 2131-8
Ravi RG, Kim HS, Servos J, et al. (2002) Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists. Journal of Medicinal Chemistry. 45: 2090-100
Kim HS, Ravi RG, Marquez VE, et al. (2002) Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors. Journal of Medicinal Chemistry. 45: 208-18
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