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Elias Lolis

1991- Pharmacology Yale University, New Haven, CT 
"Elias Lolis"

Lolis, Elias Crystallography and mutogenesis triosephosphate isomerase Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1990.

Mean distance: 9953.25


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Gregory A. Petsko grad student 1990 MIT
 (Crystallography and mutogenesis triosephosphate isomerase.)


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Jodi B. Lubetsky grad student 2002 Yale
Aristidis Sachpatzidis grad student 2002 Yale
Thomas H. Scheuermann grad student 2004 Yale
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Spiller L, Manjula R, Leissing F, et al. (2023) Plant MDL proteins synergize with the cytokine MIF at CXCR2 and CXCR4 receptors in human cells. Science Signaling. 16: eadg2621
Chen E, Widjaja V, Kyro G, et al. (2023) Mapping N- to C-terminal Allosteric Coupling through Disruption of a Putative CD74 Activation Site in D-dopachrome Tautomerase. The Journal of Biological Chemistry. 104729
Shillingford S, Zhang L, Surovtseva Y, et al. (2022) A novel site on dual-specificity phosphatase MKP7/DUSP16 is required for catalysis and MAPK binding. The Journal of Biological Chemistry. 102617
Skeens E, Pantouris G, Shah D, et al. (2022) A Cysteine Variant at an Allosteric Site Alters MIF Dynamics and Biological Function in Homo- and Heterotrimeric Assemblies. Frontiers in Molecular Biosciences. 9: 783669
Chen E, Reiss K, Shah D, et al. (2021) A Structurally Preserved Allosteric Site in the MIF Superfamily Affects Enzymatic Activity and CD74 Activation in D-dopachrome Tautomerase. The Journal of Biological Chemistry. 101061
Gannam ZTK, Min K, Shillingford SR, et al. (2020) An allosteric site on MKP5 reveals a strategy for small-molecule inhibition. Science Signaling. 13
Murphy JW, Rajasekaran D, Merkel J, et al. (2020) High-Throughput Screening of a Functional Human CXCL12-CXCR4 Signaling Axis in a Genetically Modified : Discovery of a Novel Up-Regulator of CXCR4 Activity. Frontiers in Molecular Biosciences. 7: 164
Tilstam PV, Pantouris G, Corman M, et al. (2019) A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity. The Journal of Biological Chemistry
Pantouris G, Bucala R, Lolis EJ. (2018) Structural Plasticity at the C-terminal Region of Macrophage Migration Inhibitory Factor-2 Is Associated with an Induced Fit Mechanism for a Selective inhibitor. Biochemistry
Lacy M, Kontos C, Brandhofer M, et al. (2018) Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4. Scientific Reports. 8: 5171
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