Elias Lolis
Affiliations: | 1991- | Pharmacology | Yale University, New Haven, CT |
Area:
BiochemistryWebsite:
https://medicine.yale.edu/pharm/people/elias_lolis.profileGoogle:
"Elias Lolis"Bio:
Lolis, Elias Crystallography and mutogenesis triosephosphate isomerase Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1990.
Mean distance: 9953.25
Parents
Sign in to add mentor| Gregory A. Petsko | grad student | 1990 | MIT | |
| (Crystallography and mutogenesis triosephosphate isomerase.) | ||||
Children
Sign in to add trainee| Jodi B. Lubetsky | grad student | 2002 | Yale |
| Aristidis Sachpatzidis | grad student | 2002 | Yale |
| Thomas H. Scheuermann | grad student | 2004 | Yale |
BETA: Related publications
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Publications
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| Spiller L, Manjula R, Leissing F, et al. (2023) Plant MDL proteins synergize with the cytokine MIF at CXCR2 and CXCR4 receptors in human cells. Science Signaling. 16: eadg2621 |
| Chen E, Widjaja V, Kyro G, et al. (2023) Mapping N- to C-terminal Allosteric Coupling through Disruption of a Putative CD74 Activation Site in D-dopachrome Tautomerase. The Journal of Biological Chemistry. 104729 |
| Shillingford S, Zhang L, Surovtseva Y, et al. (2022) A novel site on dual-specificity phosphatase MKP7/DUSP16 is required for catalysis and MAPK binding. The Journal of Biological Chemistry. 102617 |
| Skeens E, Pantouris G, Shah D, et al. (2022) A Cysteine Variant at an Allosteric Site Alters MIF Dynamics and Biological Function in Homo- and Heterotrimeric Assemblies. Frontiers in Molecular Biosciences. 9: 783669 |
| Chen E, Reiss K, Shah D, et al. (2021) A Structurally Preserved Allosteric Site in the MIF Superfamily Affects Enzymatic Activity and CD74 Activation in D-dopachrome Tautomerase. The Journal of Biological Chemistry. 101061 |
| Gannam ZTK, Min K, Shillingford SR, et al. (2020) An allosteric site on MKP5 reveals a strategy for small-molecule inhibition. Science Signaling. 13 |
| Murphy JW, Rajasekaran D, Merkel J, et al. (2020) High-Throughput Screening of a Functional Human CXCL12-CXCR4 Signaling Axis in a Genetically Modified : Discovery of a Novel Up-Regulator of CXCR4 Activity. Frontiers in Molecular Biosciences. 7: 164 |
| Tilstam PV, Pantouris G, Corman M, et al. (2019) A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity. The Journal of Biological Chemistry |
| Pantouris G, Bucala R, Lolis EJ. (2018) Structural Plasticity at the C-terminal Region of Macrophage Migration Inhibitory Factor-2 Is Associated with an Induced Fit Mechanism for a Selective inhibitor. Biochemistry |
| Lacy M, Kontos C, Brandhofer M, et al. (2018) Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4. Scientific Reports. 8: 5171 |