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Jerry Lee Workman

1992-2003 Pennsylvania State University, State College, PA, United States 
 2003- Stowers Institute for Medical Research, Kansas City, MO, United States 
Molecular Biology, Biochemistry
"Jerry Lee Workman"

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John Preston Langmore grad student 1985 University of Michigan
 (Isolation of specific genes as chromatin (histones, fractionation, active, regulation, transcription).)
Robert E. Kingston post-doc Harvard Medical School
Robert Roeder post-doc Rockefeller
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Bhattacharya S, Reddy D, Zhang N, et al. (2022) Elevated levels of the methyltransferase SETD2 causes transcription and alternative splicing changes resulting in oncogenic phenotypes. Frontiers in Cell and Developmental Biology. 10: 945668
Amigo R, Farkas C, Gidi C, et al. (2021) The linker histone Hho1 modulates the activity of ATP-dependent chromatin remodeling complexes. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194781
Soffers JHM, Alcantara SG, Li X, et al. (2021) The SAGA core module is critical during Drosophila oogenesis and is broadly recruited to promoters. Plos Genetics. 17: e1009668
Bhattacharya S, Wang S, Reddy D, et al. (2021) Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing. Nature Communications. 12: 6452
Suganuma T, Workman JL. (2021) Nucleotide Metabolism Behind Epigenetics. Frontiers in Endocrinology. 12: 731648
Bhattacharya S, Lange JJ, Levy M, et al. (2021) The disordered regions of the methyltransferase SETD2 govern its function by regulating its proteolysis and phase separation. The Journal of Biological Chemistry. 101075
Chen W, Yu X, Wu Y, et al. (2021) The SESAME complex regulates cell senescence through the generation of acetyl-CoA. Nature Metabolism
Bhattacharya S, Levy MJ, Zhang N, et al. (2021) The methyltransferase SETD2 couples transcription and splicing by engaging mRNA processing factors through its SHI domain. Nature Communications. 12: 1443
Zhang S, Yu X, Zhang Y, et al. (2021) Metabolic regulation of telomere silencing by SESAME complex-catalyzed H3T11 phosphorylation. Nature Communications. 12: 594
Oh S, Lee J, Swanson SK, et al. (2020) Yeast Nuak1 phosphorylates histone H3 threonine 11 in low glucose stress by the cooperation of AMPK and CK2 signaling. Elife. 9
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