☰ Chemistry Tree

Kevin J Lumb

Affiliations:			Colorado State University, Fort Collins, CO
			Janssen Pharmaceutical Companies

Area:

Biochemistry

Google:

Bio:

https://www.linkedin.com/in/kevin-lumb-6420413
http://peterkimlab.stanford.edu/alumni/

Mean distance: 13271

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Parents

Christopher M. Dobson	grad student	1991	Oxford
(NMR studies of lysozyme complexes.)
Peter S. Kim	post-doc	1991-1995	MIT

Children

Joshua N. Adkins	grad student	1995-2001	Colorado State
Kathleen M Campbell	grad student	1997-2002	Colorado State
Andrew C. Vendel	grad student	1999-2003	Colorado State

Collaborators

BETA: Related publications

Publications

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Stachel SJ, Ginnetti AT, Johnson SA, et al. (2020) Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorganic & Medicinal Chemistry Letters. 30: 127403
Allen SJ, Lumb KJ. (2020) Protein-protein interactions: a structural view of inhibition strategies and the IL-23/IL-17 axis. Advances in Protein Chemistry and Structural Biology. 121: 253-303
Lu J, Byrne N, Wang J, et al. (2017) Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40. Nature Structural & Molecular Biology
Elsen NL, Patel SB, Ford RE, et al. (2017) Insights into activity and inhibition from the crystal structure of human O-GlcNAcase. Nature Chemical Biology
Blevitt JM, Hack MD, Herman KL, et al. (2017) Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction. Journal of Medicinal Chemistry
Su HP, Rickert K, Burlein C, et al. (2016) Structural characterization of nonactive site, TrkA-selective kinase inhibitors. Proceedings of the National Academy of Sciences of the United States of America
Allen SJ, Parthasarathy G, Darke PL, et al. (2015) Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4. The Journal of Biological Chemistry
Lu J, Patel S, Sharma N, et al. (2014) Structures of kibdelomycin bound to Staphylococcus aureus GyrB and ParE showed a novel U-shaped binding mode. Acs Chemical Biology. 9: 2023-31
Elsen NL, Lu J, Parthasarathy G, et al. (2012) Mechanism of action of the cell-division inhibitor PC190723: modulation of FtsZ assembly cooperativity. Journal of the American Chemical Society. 134: 12342-5
Rickert KW, Patel SB, Allison TJ, et al. (2011) Structural basis for selective small molecule kinase inhibition of activated c-Met. The Journal of Biological Chemistry. 286: 11218-25

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