☰

Thomas R. Cech

Affiliations: 
Chemistry and Biochemistry University of Colorado, Boulder, Boulder, CO, United States 
Area:
RNA (ribozyme) catalysis
Website:
http://nobelprize.org/nobel_prizes/chemistry/laureates/1989/cech.html
Google:
"Thomas R. Cech"
Bio:

The Nobel Prize in Chemistry 1989 was awarded jointly to Sidney Altman and Thomas R. Cech "for their discovery of catalytic properties of RNA"
http://www.nasonline.org/member-directory/members/15544.html
http://cechlab.colorado.edu/
http://www.hhmi.org/research/investigators/cech_bio.html
http://www.nasonline.org/programs/awards/molecular-biology.html
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Cross-listing: PombeTree - Telomere and Telomerase Tree

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Parents

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John E. Hearst grad student 1975 UC Berkeley
 (Characterization of the most rapidly renaturing sequences in the main band DNA of the mouse (Mus musculus).)
Mary Lou Pardue post-doc 1978 MIT (FlyTree)

Children

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Guowei Fang grad student CU Boulder (Cell Biology Tree)
Ci Ji Lim grad student (Cell Biology Tree)
Daniel E. Gottschling grad student 1984 CU Boulder
Brenda L. Bass grad student 1985 CU Boulder
M K. Raghuraman grad student 1990 CU Boulder
Michael A. Tanner grad student 1992-1997 CU Boulder
Toru M. Nakamura grad student 1993-1999 CU Boulder (PombeTree)
Kara M. Juneau grad student 2000 CU Boulder (PombeTree)
Jamie M. Sperger grad student 2001 CU Boulder (PombeTree)
April J. Livengood grad student 2002 CU Boulder (PombeTree)
Anita G. Seto grad student 2002 CU Boulder (PombeTree)
Stefan Aigner grad student 2003 CU Boulder (PombeTree)
Robert L. Gottlieb grad student 2003 CU Boulder (PombeTree)
Chrysa M. Latrick grad student 2009 CU Boulder (PombeTree)
Andrew B. Dalby grad student 2014 CU Boulder (PombeTree)
Tracy M. Bryan post-doc Children's Medical Research Institute, New South Wales, Australia (Telomere and Telomerase Tree)
Katherine L. Friedman post-doc Vanderbilt (Telomere and Telomerase Tree)
Feng Guo post-doc CU Boulder
Michael B. Jarstfer post-doc UNC Chapel Hill (Telomere and Telomerase Tree)
Ming Lei post-doc University of Michigan (Telomere and Telomerase Tree)
Joachim Lingner post-doc HHMI (Telomere and Telomerase Tree)
Carolyn M. Price post-doc University of Cincinnati (Telomere and Telomerase Tree)
Anna Marie Pyle post-doc CU Boulder
Sarah Woodson post-doc Johns Hopkins
James R. Williamson post-doc 1988-1990 CU Boulder
Daniel Herschlag post-doc 1989-1992 CU Boulder
Fuyuki Ishikawa post-doc 1990-1992 CU Boulder (PombeTree)
Joseph A. Piccirilli post-doc 1989-1993 CU Boulder
Jennifer A. Doudna post-doc 1991-1994 CU Boulder
Scott A. Strobel post-doc 1992-1995 CU Boulder
Kevin M. Weeks post-doc 1992-1996 CU Boulder
Julia Promisel Cooper post-doc 1993-1996 CU Boulder (PombeTree)
Philip C. Bevilacqua post-doc 1993-1997 CU Boulder
Barbara L. Golden post-doc 1993-1998 CU Boulder
Scott K. Silverman post-doc 1997-2000 CU Boulder
John Andrew Berglund post-doc 2000-2001 CU Boulder
Peter Baumann post-doc 1998-2002 CU Boulder (PombeTree)
David C. Zappulla post-doc 2002-2008 HHMI — University of Colorado, Boulder (Telomere and Telomerase Tree)
Derek James Taylor post-doc 2008-2009 CU Boulder
Andrea J. Berman post-doc 2007-2012 CU Boulder
Jacob Schwartz post-doc 2010-2014 CU Boulder
Chen Davidovich post-doc 2010-2015 CU Boulder

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Publications

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Johnson K, Seidel JM, Cech TR. (2024) Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis. Rna (New York, N.Y.)
Cai SW, Takai H, Zaug AJ, et al. (2024) POT1 recruits and regulates CST-Polα/primase at human telomeres. Cell
Hemphill WO, Steiner HR, Kominsky JR, et al. (2024) Transcription factors ERα and Sox2 have differing multiphasic DNA and RNA binding mechanisms. Rna (New York, N.Y.)
Hemphill WO, Steiner HR, Kominsky JR, et al. (2024) Transcription factors ERα and Sox2 have differing multiphasic DNA and RNA binding mechanisms. Biorxiv : the Preprint Server For Biology
Forino NM, Woo JZ, Zaug AJ, et al. (2023) Dissecting telomerase RNA structural heterogeneity in living human cells with DMS-MaPseq. Biorxiv : the Preprint Server For Biology
Song J, Gooding AR, Hemphill WO, et al. (2023) Structural basis for inactivation of PRC2 by G-quadruplex RNA. Science (New York, N.Y.). 381: 1331-1337
Long Y, Hwang T, Gooding AR, et al. (2023) Evaluation of the RNA-dependence of PRC2 binding to chromatin in human pluripotent stem cells. Biorxiv : the Preprint Server For Biology
Hemphill WO, Voong CK, Fenske R, et al. (2023) Multiple RNA- and DNA-binding proteins exhibit direct transfer of polynucleotides with implications for target-site search. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220537120
Hemphill WO, Fenske R, Gooding AR, et al. (2023) PRC2 direct transfer from G-quadruplex RNA to dsDNA has implications for RNA-binding chromatin modifiers. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220528120
Song J, Gooding AR, Hemphill WO, et al. (2023) Structural basis for inactivation of PRC2 by G-quadruplex RNA. Biorxiv : the Preprint Server For Biology
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