Matthew M. Endo

Organic Chemistry, Chemical Biology

Joseph M. Langenhan	research assistant	2006-2008	Seattle University
Martin D. Burke	grad student	2009-	UIUC

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Davis SA, Vincent BM, Endo MM, et al. (2015) Nontoxic antimicrobials that evade drug resistance. Nature Chemical Biology. 11: 481-7
Endo MM, Cioffi AG, Burke MD. (2015) Our Path to Less Toxic Amphotericins Synlett
Wilcock BC, Endo MM, Uno BE, et al. (2013) C2'-OH of amphotericin B plays an important role in binding the primary sterol of human cells but not yeast cells. Journal of the American Chemical Society. 135: 8488-91
Gray KC, Palacios DS, Dailey I, et al. (2012) Amphotericin primarily kills yeast by simply binding ergosterol. Proceedings of the National Academy of Sciences of the United States of America. 109: 2234-9
Langenhan JM, Endo MM, Engle JM, et al. (2011) Synthesis and biological evaluation of RON-neoglycosides as tumor cytotoxins. Carbohydrate Research. 346: 2663-76
Langenhan JM, Engle JM, Slevin LK, et al. (2008) Modifying the glycosidic linkage in digitoxin analogs provides selective cytotoxins. Bioorganic & Medicinal Chemistry Letters. 18: 670-3