Mark W. Ruszczycky
Affiliations: | Biochemistry | Case Western Reserve University, Cleveland Heights, OH, United States |
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Parents
Sign in to add mentorVernon Emmett Anderson | grad student | 2006 | Case Western Medical School | |
(V/K isotope effects on enzyme catalyzed nucleophilic displacement.) |
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Publications
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Lee YH, Yeh YC, Fan PH, et al. (2023) Changing Fates of the Substrate Radicals Generated in the Active Sites of the B-Dependent Radical SAM Enzymes OxsB and AlsB. Journal of the American Chemical Society |
Zhang J, Hou X, Chen Z, et al. (2022) Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. Journal of the American Chemical Society |
Lee YH, Hou X, Chen R, et al. (2022) Radical -Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S. Journal of the American Chemical Society |
Jeon BS, Huang TY, Ruszczycky MW, et al. (2021) Byproduct formation during the biosynthesis of spinosyn A and evidence for an enzymatic interplay to prevent its formation. Tetrahedron. 103 |
Choi SH, Jeon B, Kim N, et al. (2021) Evidence for an Enzyme-Catalyzed Rauhut-Currier Reaction during the Biosynthesis of Spinosyn A. Journal of the American Chemical Society |
Besandre RA, Chen Z, Davis I, et al. (2021) HygY Is a Twitch Radical SAM Epimerase with Latent Dehydrogenase Activity Revealed upon Mutation of a Single Cysteine Residue. Journal of the American Chemical Society |
Ren D, Ruszczycky MW, Ko Y, et al. (2020) Characterization of the coformycin biosynthetic gene cluster in . Proceedings of the National Academy of Sciences of the United States of America |
Ruszczycky MW, Liu HW. (2019) Measurement of Net Rate Constants from Enzyme Progress Curves without Curve Fitting. Biochemistry |
Ushimaru R, Ruszczycky MW, Liu HW. (2018) Changes in regioselectivity of H atom abstraction during the hydroxylation and cyclization reactions catalyzed by hyoscyamine 6β-hydroxylase. Journal of the American Chemical Society |
Ushimaru R, Ruszczycky MW, Chang WC, et al. (2018) Substrate Conformation Correlates with the Outcome of Hyoscyamine 6β-Hydroxylase Catalyzed Oxidation Reactions. Journal of the American Chemical Society |