Mark W. Ruszczycky

Affiliations: 
Biochemistry Case Western Reserve University, Cleveland Heights, OH, United States 
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"Mark Ruszczycky"
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Vernon Emmett Anderson grad student 2006 Case Western Medical School
 (V/K isotope effects on enzyme catalyzed nucleophilic displacement.)
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Lee YH, Yeh YC, Fan PH, et al. (2023) Changing Fates of the Substrate Radicals Generated in the Active Sites of the B-Dependent Radical SAM Enzymes OxsB and AlsB. Journal of the American Chemical Society
Zhang J, Hou X, Chen Z, et al. (2022) Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. Journal of the American Chemical Society
Lee YH, Hou X, Chen R, et al. (2022) Radical -Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S. Journal of the American Chemical Society
Jeon BS, Huang TY, Ruszczycky MW, et al. (2021) Byproduct formation during the biosynthesis of spinosyn A and evidence for an enzymatic interplay to prevent its formation. Tetrahedron. 103
Choi SH, Jeon B, Kim N, et al. (2021) Evidence for an Enzyme-Catalyzed Rauhut-Currier Reaction during the Biosynthesis of Spinosyn A. Journal of the American Chemical Society
Besandre RA, Chen Z, Davis I, et al. (2021) HygY Is a Twitch Radical SAM Epimerase with Latent Dehydrogenase Activity Revealed upon Mutation of a Single Cysteine Residue. Journal of the American Chemical Society
Ren D, Ruszczycky MW, Ko Y, et al. (2020) Characterization of the coformycin biosynthetic gene cluster in . Proceedings of the National Academy of Sciences of the United States of America
Ruszczycky MW, Liu HW. (2019) Measurement of Net Rate Constants from Enzyme Progress Curves without Curve Fitting. Biochemistry
Ushimaru R, Ruszczycky MW, Liu HW. (2018) Changes in regioselectivity of H atom abstraction during the hydroxylation and cyclization reactions catalyzed by hyoscyamine 6β-hydroxylase. Journal of the American Chemical Society
Ushimaru R, Ruszczycky MW, Chang WC, et al. (2018) Substrate Conformation Correlates with the Outcome of Hyoscyamine 6β-Hydroxylase Catalyzed Oxidation Reactions. Journal of the American Chemical Society
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