Michael Topal

University of North Carolina, Chapel Hill, Chapel Hill, NC 
"Michael Topal"
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Koboldt DC, Fulton RS, McLellan MD, et al. (2012) Comprehensive molecular portraits of human breast tumours Nature. 490: 61-70
Ruggiero BL, Topal MD. (2004) Triplet repeat expansion generated by DNA slippage is suppressed by human flap endonuclease 1. The Journal of Biological Chemistry. 279: 23088-97
Heidenfelder BL, Topal MD. (2003) Effects of sequence on repeat expansion during DNA replication. Nucleic Acids Research. 31: 7159-64
Carrick KL, Topal MD. (2003) Amino acid substitutions at position 43 of NaeI endonuclease. Evidence for changes in NaeI structure. The Journal of Biological Chemistry. 278: 9733-9
Heidenfelder BL, Makhov AM, Topal MD. (2003) Hairpin formation in Friedreich's ataxia triplet repeat expansion. The Journal of Biological Chemistry. 278: 2425-31
Huai Q, Colandene JD, Topal MD, et al. (2001) Structure of NaeI-DNA complex reveals dual-mode DNA recognition and complete dimer rearrangement. Nature Structural Biology. 8: 665-9
Colandene JD, Topal MD. (2000) Evidence for mutations that break communication between the Endo and Topo domains in NaeI endonuclease/topoisomerase. Biochemistry. 39: 13703-7
Huai Q, Colandene JD, Chen Y, et al. (2000) Crystal structure of NaeI-an evolutionary bridge between DNA endonuclease and topoisomerase. The Embo Journal. 19: 3110-8
Lyons-Darden T, Topal MD. (1999) Abasic sites induce triplet-repeat expansion during DNA replication in vitro. The Journal of Biological Chemistry. 274: 25975-8
Lyons-Darden T, Topal MD. (1999) Effects of temperature, Mg2+ concentration and mismatches on triplet-repeat expansion during DNA replication in vitro. Nucleic Acids Research. 27: 2235-40
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