Geqing Chai, Ph.D.

Affiliations: 
2004 University of South Carolina, Columbia, SC 
Area:
Biochemistry, Pharmaceutical Chemistry, Physical Chemistry
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"Geqing Chai"
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Lukasz Lebioda grad student 2004 University of South Carolina
 (Human neuron specific enolase, chicken/human annexin V, formyltetrahydrofolate synthetase: Structural and mechanistic study.)
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Publications

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Qin J, Chai G, Brewer JM, et al. (2012) Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity. Journal of Inorganic Biochemistry. 111: 187-94
Celeste LR, Chai G, Bielak M, et al. (2012) Mechanism of N10-formyltetrahydrofolate synthetase derived from complexes with intermediates and inhibitors. Protein Science : a Publication of the Protein Society. 21: 219-28
Qin J, Chai G, Brewer JM, et al. (2006) Fluoride inhibition of enolase: crystal structure and thermodynamics. Biochemistry. 45: 793-800
Chai G, Brewer JM, Lovelace LL, et al. (2004) Expression, purification and the 1.8 angstroms resolution crystal structure of human neuron specific enolase. Journal of Molecular Biology. 341: 1015-21
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