Geqing Chai, Ph.D.
|2004||University of South Carolina, Columbia, SC|
Area:Biochemistry, Pharmaceutical Chemistry, Physical Chemistry
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|Qin J, Chai G, Brewer JM, et al. (2012) Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity. Journal of Inorganic Biochemistry. 111: 187-94|
|Celeste LR, Chai G, Bielak M, et al. (2012) Mechanism of N10-formyltetrahydrofolate synthetase derived from complexes with intermediates and inhibitors. Protein Science : a Publication of the Protein Society. 21: 219-28|
|Bokinsky G, Nivón LG, Liu S, et al. (2006) Two distinct binding modes of a protein cofactor with its target RNA. Journal of Molecular Biology. 361: 771-84|
|Qin J, Chai G, Brewer JM, et al. (2006) Fluoride inhibition of enolase: crystal structure and thermodynamics. Biochemistry. 45: 793-800|
|Chai G, Brewer JM, Lovelace LL, et al. (2004) Expression, purification and the 1.8 angstroms resolution crystal structure of human neuron specific enolase. Journal of Molecular Biology. 341: 1015-21|