☰ Chemistry Tree

Thomas L. James

Affiliations:

Chemistry

University of California, San Francisco, San Francisco, CA

Area:

Pharmaceutical Chemistry

Website:

http://www.jameslab.ucsf.edu/research.html

Google:

Bio:

https://books.google.com/books?id=-4ecAAAAMAAJ

Mean distance: 9.35 (cluster 10)

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Parents

Richard Joseph Kula	grad student	1969	UW Madison
Joseph H. Noggle	grad student	1969	UW Madison
(Nuclear Magnetic Resonance of Metal Ion Complexes.)

Children

Alan P. Koretsky	grad student	1984	UC Berkeley
David E. Konerding	grad student	2001	UCSF
Marco Tonelli	grad student	2003	UCSF
Samuel P. Sawan	post-doc	1976-1978	UCSF

Collaborators

BETA: Related publications

Publications

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Chimenti MS, Bulfer SL, Neitz RJ, et al. (2015) A Fragment-Based Ligand Screen Against Part of a Large Protein Machine: The ND1 Domains of the AAA+ ATPase p97/VCP. Journal of Biomolecular Screening. 20: 788-800
Liu J, Litt L, Segal MR, et al. (2011) Outcome-related metabolomic patterns from 1H/31P NMR after mild hypothermia treatments of oxygen-glucose deprivation in a neonatal brain slice model of asphyxia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 547-59
Chung J, Ulyanov NB, Guilbert C, et al. (2010) Binding characteristics of small molecules that mimic nucleocapsid protein-induced maturation of stem-loop 1 of HIV-1 RNA. Biochemistry. 49: 6341-51
Pellecchia M, Bertini I, Cowburn D, et al. (2008) Perspectives on NMR in drug discovery: a technique comes of age. Nature Reviews. Drug Discovery. 7: 738-45
Du Z, Fenn S, Tjhen R, et al. (2008) Structure of a construct of a human poly(C)-binding protein containing the first and second KH domains reveals insights into its regulatory mechanisms. The Journal of Biological Chemistry. 283: 28757-66
Zeng J, Liu J, Yang GY, et al. (2007) Exogenous ethyl pyruvate versus pyruvate during metabolic recovery after oxidative stress in neonatal rat cerebrocortical slices. Anesthesiology. 107: 630-40
Du Z, Lee JK, Fenn S, et al. (2007) X-ray crystallographic and NMR studies of protein-protein and protein-nucleic acid interactions involving the KH domains from human poly(C)-binding protein-2. Rna (New York, N.Y.). 13: 1043-51
Du Z, Fenn S, James TL. (2007) Resonance assignment of the first and second KH (hnRNP-K homology) domains of human poly(C)-binding protein-2 (PCBP2). Journal of Biomolecular Nmr. 38: 197
Fenn S, Du Z, Lee JK, et al. (2007) Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution. Nucleic Acids Research. 35: 2651-60
Mayer M, Lang PT, Gerber S, et al. (2006) Synthesis and testing of a focused phenothiazine library for binding to HIV-1 TAR RNA. Chemistry & Biology. 13: 993-1000

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