Stephen R. Brych, Ph.D.

Affiliations: 
2004 Florida State University, Tallahassee, FL, United States 
Area:
Biochemistry
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Michael Blaber grad student 1999-2004 Florida State
 (A redesigned hydrophobic core of a symmetric protein superfold with increased primary structure symmetry.)
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Publications

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Kim J, Lee J, Brych SR, et al. (2005) Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor. Protein Science : a Publication of the Protein Society. 14: 351-9
Brych SR, Dubey VK, Bienkiewicz E, et al. (2004) Symmetric primary and tertiary structure mutations within a symmetric superfold: a solution, not a constraint, to achieve a foldable polypeptide. Journal of Molecular Biology. 344: 769-80
Brych SR, Kim J, Logan TM, et al. (2003) Accommodation of a highly symmetric core within a symmetric protein superfold. Protein Science : a Publication of the Protein Society. 12: 2704-18
Kim J, Brych SR, Lee J, et al. (2003) Identification of a key structural element for protein folding within beta-hairpin turns. Journal of Molecular Biology. 328: 951-61
Brych SR, Blaber SI, Logan TM, et al. (2001) Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil. Protein Science : a Publication of the Protein Society. 10: 2587-99
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