Hanumantharao Paritala

Affiliations: 
Wayne State University, Detroit, MI, United States 
Area:
Medicinal chemistry, Chemical biology, Biochemsitry
Website:
http://digitalcommons.wayne.edu/oa_dissertations/26/
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"Hanumantharao Paritala"
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Parents

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Steven M. Firestine grad student 2010 Wayne State
 (Enzymology and medicinal chemistry of N5-carboxyaminoimidazole ribonucleotide synthetase: A novel antibacterial target.)
Kate S. Carroll post-doc 2010-2016 The Scripps Research Institute, Scripps Florida
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Publications

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Paritala H, Palde PB, Carroll KS. (2016) Functional Site Discovery in a Sulphur Metabolism Enzyme Using Directed Evolution. Chembiochem : a European Journal of Chemical Biology
Gupta V, Paritala H, Carroll KS. (2016) Reactivity, Selectivity and Stability in Sulfenic Acid Detection: A Comparative Study of Nucleophilic and Electropilic Probes. Bioconjugate Chemistry
Paritala H, Suzuki Y, Carroll KS. (2015) Design, synthesis and evaluation of Fe-S targeted adenosine 5'-phosphosulfate reductase inhibitors. Nucleosides, Nucleotides & Nucleic Acids. 34: 199-220
Paritala H, Carroll KS. (2013) New targets and inhibitors of mycobacterial sulfur metabolism. Infectious Disorders Drug Targets. 13: 85-115
Paritala H, Suzuki Y, Carroll KS. (2013) Efficient microwave-assisted solid phase coupling of nucleosides, small library generation and mild conditions for release of nucleoside derivatives. Tetrahedron Letters. 54: 1869-1872
Paritala H, Carroll KS. (2013) A continuous spectrophotometric assay for adenosine 5'-phosphosulfate reductase activity with sulfite-selective probes. Analytical Biochemistry. 440: 32-9
Paritala H, Firestine SM. (2010) Characterization of insulin ILPR sequences for their ability to adopt a G-quadruplex structure. Nucleosides, Nucleotides & Nucleic Acids. 29: 81-90
Thoden JB, Holden HM, Paritala H, et al. (2010) Structural and functional studies of Aspergillus clavatus N(5)-carboxyaminoimidazole ribonucleotide synthetase . Biochemistry. 49: 752-60
Firestine SM, Paritala H, McDonnell JE, et al. (2009) Identification of inhibitors of N5-carboxyaminoimidazole ribonucleotide synthetase by high-throughput screening. Bioorganic & Medicinal Chemistry. 17: 3317-23
Paritala H, Firestine SM. (2009) Benzo(h)quinoline derivatives as G-quadruplex binding agents. Bioorganic & Medicinal Chemistry Letters. 19: 1584-7
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