Bertrand Garcia-Moreno

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
General Biophysics, Biochemistry
Website:
https://biophysics.jhu.edu/directory/bertrand-garcia-moreno/
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"Bertrand Garcia-Moreno"
Bio:

https://pmb.jhu.edu/directory/bertrand-garcia-moreno/

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Parents

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Frank R.N. Gurd grad student 1986 Indiana University
 (Effects of ion binding and electrostatic interactions on the structure and function of sperm whale myoglobin.)
Gary Keith Ackers post-doc Johns Hopkins (Physics Tree)

Children

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Joshua A. Riback research assistant 2013 Johns Hopkins
Steven T. Whitten grad student 2000 Johns Hopkins
Daniel G. Isom grad student 2006 Johns Hopkins
Brian R. Cannon grad student 2008 Johns Hopkins
Daniel A. Karp grad student 2008 Johns Hopkins
Carlos A. Castaneda grad student 2009 Johns Hopkins
Ignacia Echeverria grad student 2011 Johns Hopkins
BETA: Related publications

Publications

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Isom DG, Castañeda CA, Cannon BR, et al. (2011) Large shifts in pKa values of lysine residues buried inside a protein. Proceedings of the National Academy of Sciences of the United States of America. 108: 5260-5
Kitahara R, Hata K, Maeno A, et al. (2011) Structural plasticity of staphylococcal nuclease probed by perturbation with pressure and pH. Proteins. 79: 1293-305
Isom DG, Castañeda CA, Cannon BR, et al. (2010) Charges in the hydrophobic interior of proteins. Proceedings of the National Academy of Sciences of the United States of America. 107: 16096-100
Karp DA, Stahley MR, García-Moreno B. (2010) Conformational consequences of ionization of Lys, Asp, and Glu buried at position 66 in staphylococcal nuclease. Biochemistry. 49: 4138-46
Isom DG, Cannon BR, Castañeda CA, et al. (2008) High tolerance for ionizable residues in the hydrophobic interior of proteins. Proceedings of the National Academy of Sciences of the United States of America. 105: 17784-8
Schlessman JL, Abe C, Gittis A, et al. (2008) Crystallographic study of hydration of an internal cavity in engineered proteins with buried polar or ionizable groups. Biophysical Journal. 94: 3208-16
Whitten ST, García-Moreno BE, Hilser VJ. (2008) Ligand effects on the protein ensemble: unifying the descriptions of ligand binding, local conformational fluctuations, and protein stability. Methods in Cell Biology. 84: 871-91
Hilser VJ, García-Moreno E B, Oas TG, et al. (2006) A statistical thermodynamic model of the protein ensemble. Chemical Reviews. 106: 1545-58
Fitch CA, Whitten ST, Hilser VJ, et al. (2006) Molecular mechanisms of pH-driven conformational transitions of proteins: insights from continuum electrostatics calculations of acid unfolding. Proteins. 63: 113-26
Whitten ST, García-Moreno E B, Hilser VJ. (2005) Local conformational fluctuations can modulate the coupling between proton binding and global structural transitions in proteins. Proceedings of the National Academy of Sciences of the United States of America. 102: 4282-7
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