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Joyce Hamlin

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Biochemistry
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"Joyce Hamlin"
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Parents

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Children

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Xiaomei Li grad student 2000 UVA
Yujie Shan grad student 2000 UVA
LeeAnn O. Swanegan grad student 2002 UVA
Jane Azizkhan-Clifford post-doc (Microtree)

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Publications

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Lin HB, Dijkwel PA, Hamlin JL. (2005) Promiscuous initiation on mammalian chromosomal DNA templates and its possible suppression by transcription. Experimental Cell Research. 308: 53-64
Mesner LD, Hamlin JL. (2005) Specific signals at the 3' end of the DHFR gene define one boundary of the downstream origin of replication. Genes & Development. 19: 1053-66
Saha S, Shan Y, Mesner LD, et al. (2004) The promoter of the Chinese hamster ovary dihydrofolate reductase gene regulates the activity of the local origin and helps define its boundaries. Genes & Development. 18: 397-410
Mesner LD, Li X, Dijkwel PA, et al. (2003) The dihydrofolate reductase origin of replication does not contain any nonredundant genetic elements required for origin activity. Molecular and Cellular Biology. 23: 804-14
Dijkwel PA, Wang S, Hamlin JL. (2002) Initiation sites are distributed at frequent intervals in the Chinese hamster dihydrofolate reductase origin of replication but are used with very different efficiencies. Molecular and Cellular Biology. 22: 3053-65
Alexandrow MG, Ritzi M, Pemov A, et al. (2002) A potential role for mini-chromosome maintenance (MCM) proteins in initiation at the dihydrofolate reductase replication origin. The Journal of Biological Chemistry. 277: 2702-8
Dijkwel PA, Mesner LD, Levenson VV, et al. (2000) Dispersive initiation of replication in the Chinese hamster rhodopsin locus. Experimental Cell Research. 256: 150-7
Kalejta RF, Li X, Mesner LD, et al. (1998) Distal sequences, but not ori-beta/OBR-1, are essential for initiation of DNA replication in the Chinese hamster DHFR origin. Molecular Cell. 2: 797-806
Wang S, Dijkwel PA, Hamlin JL. (1998) Lagging-strand, early-labelling, and two-dimensional gel assays suggest multiple potential initiation sites in the Chinese hamster dihydrofolate reductase origin. Molecular and Cellular Biology. 18: 39-50
Dijkwel PA, Vaughn JP, Hamlin JL. (1994) Replication initiation sites are distributed widely in the amplified CHO dihydrofolate reductase domain. Nucleic Acids Research. 22: 4989-96
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