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Katsuhiko Murakami

Affiliations: 
2003- Biochemistry, Microbiology, and Molecular Biology Pennsylvania State University, State College, PA, United States 
Area:
Microbiology Biology, Genetics, Molecular Biology, Structural Biology
Website:
http://rnaplab.org
Google:
"Katsuhiko Murakami"
Bio:

Katsuhiko Murakami started his research career as a graduate student working under Prof. Akira Ishihama in the National Institute of Genetics and the Graduate University of Advanced Studies in Japan. His thesis title is “Functional analysis of the carboxyl-terminal transcription regulation domain of Escherichia coli RNA polymerase α subunit” and he received Ph. D. in 1997. He engaged in postdoctoral study at the Rockefeller University (1998-2003) for determining the X-ray crystal structure of bacterial RNA polymerase. He joined the Department of Biochemistry and Molecular Biology at Pennsylvania State University as an Assistant Professor in 2003 and became a full Professor in 2015.

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Parents

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Akira Ishihama grad student 1994-1997 National Institute of Genetics in Mishima (Neurotree)
Seth A. Darst post-doc 1998-2003 Rockefeller (Chemistry Tree)

Children

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Rieko Yajima grad student (Chemistry Tree)
Michael L. Gleghorn grad student 2008 Penn State
Momoko Tajiri grad student 2008 Penn State

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BETA: Related publications

Publications

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Qayyum MZ, Imashimizu M, Leanca M, et al. (2024) Structure and function of the Si3 insertion integrated into the trigger loop/helix of cyanobacterial RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 121: e2311480121
Qayyum MZ, Imashimizu M, Leanca M, et al. (2024) Structure and function of the Si3 insertion integrated into the trigger loop/helix of cyanobacterial RNA polymerase. Biorxiv : the Preprint Server For Biology
Vishwakarma RK, Qayyum MZ, Babitzke P, et al. (2023) Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 120: e2218516120
Lisitskaya L, Shin Y, Agapov A, et al. (2022) Author Correction: Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity. Nature Communications. 13: 4839
Lisitskaya L, Shin Y, Agapov A, et al. (2022) Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity. Nature Communications. 13: 4624
Marshall CJ, Qayyum MZ, Walker JE, et al. (2022) The structure and activities of the archaeal transcription termination factor Eta detail vulnerabilities of the transcription elongation complex. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207581119
Portman JR, Qayyum MZ, Murakami KS, et al. (2022) On the stability of stalled RNA polymerase and its removal by RapA. Nucleic Acids Research. 50: 7396-7405
Qayyum MZ, Molodtsov V, Renda A, et al. (2021) Structural basis of RNA polymerase recycling by the Swi2/Snf2 family of ATPase RapA in Escherichia coli. The Journal of Biological Chemistry. 297: 101404
Shin Y, Murakami KS. (2021) Watching the bacterial RNA polymerase transcription reaction by time-dependent soak-trigger-freeze X-ray crystallography. The Enzymes. 49: 305-314
Mäkinen JJ, Shin Y, Vieras E, et al. (2021) The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases. Nature Communications. 12: 796
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