Kevin J. Gingrich

Affiliations: 
University of Rochester, Rochester, NY 
Area:
Pharmacology, Biochemistry
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"Kevin Gingrich"
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Publications

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Gingrich KJ, Wagner LE. (2016) Fast-onset lidocaine block of rat NaV1.4 channels suggests involvement of a second high-affinity open state. Biochimica Et Biophysica Acta. 1858: 1175-1188
Purtell K, Gingrich KJ, Ouyang W, et al. (2015) Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane. British Journal of Anaesthesia. 115: 112-21
Schober A, Sokolova E, Gingrich KJ. (2010) Pentobarbital inhibition of human recombinant α 1A P/Q-type voltage-gated calcium channels involves slow, open channel block British Journal of Pharmacology. 161: 365-383
Atack JR, Maubach KA, Wafford KA, et al. (2009) In vitro and in vivo properties of 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)-pyrazolo[1,5-d]-[1,2,4]triazine (MRK-016), a GABAA receptor alpha5 subtype-selective inverse agonist. The Journal of Pharmacology and Experimental Therapeutics. 331: 470-84
Gingrich KJ, Burkat PM, Roberts WA. (2009) Pentobarbital produces activation and block of {alpha}1{beta}2{gamma}2S GABAA receptors in rapidly perfused whole cells and membrane patches: divergent results can be explained by pharmacokinetics. The Journal of General Physiology. 133: 171-88
Gingrich KJ, Yang J. (2006) Molecular physiology Foundations of Anesthesia. 79-89
Gingrich KJ, Tran S, Nikonorov IM, et al. (2005) Halothane inhibition of recombinant cardiac L-type Ca2+ channels expressed in HEK-293 cells. Anesthesiology. 103: 1156-66
Wagner LE, Gingrich KJ, Kulli JC, et al. (2001) Ketamine blockade of voltage-gated sodium channels: Evidence for a shared receptor site with local anesthetics Anesthesiology. 95: 1406-1413
Burkat PM, Yang J, Gingrich KJ. (2001) Dominant gating governing transient GABA(A) receptor activity: a first latency and Po/o analysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7026-36
Kimbrough JT, Gingrich KJ. (2000) Quaternary ammonium block of mutant Na+ channels lacking inactivation: features of a transition-intermediate mechanism. The Journal of Physiology. 529: 93-106
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