David S. Askew

University of Cincinnati, Cincinnati, OH 
Cell Biology, Molecular Biology, Microbiology Biology, Biochemistry
"David Stephen Askew"


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Fumio Takei grad student 1985 UBC (Cell Biology Tree)
 (Characterization of novel myeloid differentiation antigen associated with acute myelogenous leukemia.)
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Raj S, Krishnan K, Askew DS, et al. (2015) Toxicity of a novel antifungal compound is modulated by ERAD components. Antimicrobial Agents and Chemotherapy
Askew DS, Kontoyiannis DP, Clemons KV. (2014) Advances against aspergillosis: biology, host response, diagnosis and treatment. Mycopathologia. 178: 321-4
Krishnan K, Ren Z, Losada L, et al. (2014) Polysome profiling reveals broad translatome remodeling during endoplasmic reticulum (ER) stress in the pathogenic fungus Aspergillus fumigatus. Bmc Genomics. 15: 159
Askew DS. (2014) Endoplasmic reticulum stress and fungal pathogenesis converge. Virulence. 5: 331-3
Krishnan K, Askew DS. (2014) The fungal UPR: a regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus. Virulence. 5: 334-40
Powers-Fletcher MV, Feng X, Krishnan K, et al. (2013) Deletion of the sec4 homolog srgA from Aspergillus fumigatus is associated with an impaired stress response, attenuated virulence and phenotypic heterogeneity. Plos One. 8: e66741
Jambunathan K, Watson DS, Najvar LK, et al. (2013) Prolyl endopeptidase activity in bronchoalveolar lavage fluid: a novel diagnostic biomarker in a guinea pig model of invasive pulmonary aspergillosis. Medical Mycology. 51: 592-602
Krishnan K, Feng X, Powers-Fletcher MV, et al. (2013) Effects of a defective endoplasmic reticulum-associated degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the mold pathogen Aspergillus fumigatus. Eukaryotic Cell. 12: 512-9
Gravelat FN, Askew DS, Sheppard DC. (2012) Targeted gene deletion in Aspergillus fumigatus using the hygromycin-resistance split-marker approach. Methods in Molecular Biology (Clifton, N.J.). 845: 119-30
Powers-Fletcher MV, Jambunathan K, Brewer JL, et al. (2011) Impact of the lectin chaperone calnexin on the stress response, virulence and proteolytic secretome of the fungal pathogen Aspergillus fumigatus. Plos One. 6: e28865
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