William E. Royer

Affiliations: 
Clark University, Worcester, MA, United States 
Area:
Biochemistry
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"William Royer"
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Publications

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Korwar S, Morris BL, Parikh HI, et al. (2016) Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP). Bioorganic & Medicinal Chemistry
Hilbert BJ, Morris BL, Ellis KC, et al. (2015) Structure-guided design of a high affinity inhibitor to human CtBP. Acs Chemical Biology. 10: 1118-27
Laine JM, Amat M, Morgan BR, et al. (2014) Insight into the allosteric mechanism of Scapharca dimeric hemoglobin. Biochemistry. 53: 7199-210
Hilbert BJ, Grossman SR, Schiffer CA, et al. (2014) Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design. Febs Letters. 588: 1743-8
Ren Z, Chan PW, Moffat K, et al. (2013) Resolution of structural heterogeneity in dynamic crystallography. Acta Crystallographica. Section D, Biological Crystallography. 69: 946-59
Ronda L, Bettati S, Henry ER, et al. (2013) Tertiary and quaternary allostery in tetrameric hemoglobin from Scapharca inaequivalvis. Biochemistry. 52: 2108-17
Ren Z, Šrajer V, Knapp JE, et al. (2012) Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures Proceedings of the National Academy of Sciences of the United States of America. 109: 107-112
Romano KP, Ali A, Royer WE, et al. (2010) Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding. Proceedings of the National Academy of Sciences of the United States of America. 107: 20986-91
Shandilya SM, Nalam MN, Nalivaika EA, et al. (2010) Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces. Structure (London, England : 1993). 18: 28-38
Choi J, Muniyappan S, Wallis JT, et al. (2010) Protein conformational dynamics of homodimeric hemoglobin revealed by combined time-resolved spectroscopic probes. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 11: 109-14
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