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Emil F. Pai

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Microbiology Biology, Biochemistry
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"Emil Pai"
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Parents

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Georg E. Schulz grad student MPI for Medical Research
Heinz A. Staab grad student Universität Heidelberg

Children

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Michelle A Sahai grad student University of Toronto
Piotr Sliz grad student 2000 University of Toronto
Matthew S. Kimber grad student 2001 University of Guelph (Canada)
Vivian C. Saridakis grad student 2002 York University
Shekeb Khan grad student 2012 University of Toronto
Braden Sweeting grad student 2013 University of Toronto
Patricia Ellison post-doc University of Nevada at Reno
Ute Krengel post-doc University of Oslo, Norway

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Publications

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Mehrabi P, Schulz EC, Dsouza R, et al. (2019) Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science (New York, N.Y.). 365: 1167-1170
De Gasparo R, Halgas O, Harangozo D, et al. (2019) Targeting a Large Active Site: Structure-Based Design of Nanomolar Inhibitors of Trypanosoma brucei Trypanothione Reductase. Chemistry (Weinheim An Der Bergstrasse, Germany)
Mehrabi P, Di Pietrantonio C, Kim TH, et al. (2019) Substrate-based Allosteric Regulation of a Homodimeric Enzyme. Journal of the American Chemical Society
Ishizawa J, Zarabi SF, Davis RE, et al. (2019) Abstract 2720: Mitochondrial ClpP-mediated proteolysis induces selective cancer cell lethality Cancer Research. 79: 2720-2720
Schulz EC, Mehrabi P, Müller-Werkmeister HM, et al. (2018) The hit-and-return system enables efficient time-resolved serial synchrotron crystallography. Nature Methods. 15: 901-904
De Gasparo R, Brodbeck-Persch E, Bryson S, et al. (2018) Biological Evaluation and X-ray Co-crystal Structures of Cyclohexylpyrrolidine Ligands for Trypanothione Reductase, an Enzyme from the Redox Metabolism of Trypanosoma. Chemmedchem
Mehrabi P, Schulz E, Müller-Werkmeister HM, et al. (2018) Time-resolved crystallography via an interlacing approach allows elucidation of milliseconds to seconds time delays Acta Crystallographica Section a Foundations and Advances. 74: e138-e138
Mehrabi P, Schulz EC, Müller-Werkmeister HM, et al. (2018) Time-resolved serial synchrotron crystallography: an efficient interlacing system enables milliseconds to seconds time delays Acta Crystallographica Section a Foundations and Advances. 74: a53-a53
Kim TH, Mehrabi P, Ren Z, et al. (2017) The role of dimer asymmetry and protomer dynamics in enzyme catalysis. Science (New York, N.Y.). 355
Chirgadze YN, Boshkova EA, Battaile KP, et al. (2016) Crystal structure of Staphylococcus aureus Zn-glyoxalase I: new subfamily of glyoxalase I family. Journal of Biomolecular Structure & Dynamics. 1-26
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